Evidence map›Paper›PMID 33475843›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021

ISSLS Prize in Bioengineering Science 2021: in vivo sagittal motion of the lumbar spine in low back pain patients-a radiological big data study.

Fabio Galbusera, Frank Niemeyer, Youping Tao, Andrea Cina, Luca Maria Sconfienza, Annette Kienle, Hans-Joachim Wilke

Abstract read
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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. The effect of various options for decompression of degenerated lumbar spine motion segments on the range of motion: a biomechanical in vitro study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fabio GalbuseraLaboratory of Biological Structures Mechanics, IRCCS Istituto Ortopedico Galeazzi, viale Galeazzi 4, 20161, Milan, Italy. fabio.galbusera@grupposandonato.it.ORCID http://orcid.org/0000-0003-1826-9190
Frank NiemeyerInstitute of Orthopaedic Research and Biomechanics, Center for Trauma Research Ulm, Ulm University, Ulm, Germany.
Youping TaoInstitute of Orthopaedic Research and Biomechanics, Center for Trauma Research Ulm, Ulm University, Ulm, Germany.
Andrea CinaLaboratory of Biological Structures Mechanics, IRCCS Istituto Ortopedico Galeazzi, viale Galeazzi 4, 20161, Milan, Italy.
Luca Maria SconfienzaLaboratory of Biological Structures Mechanics, IRCCS Istituto Ortopedico Galeazzi, viale Galeazzi 4, 20161, Milan, Italy.
Annette KienleSpineServ GmbH, Ulm, Germany.
Hans-Joachim WilkeInstitute of Orthopaedic Research and Biomechanics, Center for Trauma Research Ulm, Ulm University, Ulm, Germany.

Funding

Ministero della Salute Ricerca Corrente
6 · The paper itself

Abstract

purposeWe investigated the flexion-extension range of motion and centre of rotation of lumbar motion segments in a large population of 602 patients (3612 levels), and the associations between lumbar motion and other parameters such as sex, age and intervertebral disc degeneration.

methodsLumbar radiographs in flexion-extension of 602 patients suffering from low back pain and/or suspect instability were collected; magnetic resonance images were retrieved and used to score the degree of disc degeneration for a subgroup of 354 patients. Range of motion and centre of rotation were calculated for all lumbosacral levels with in-house software allowing for high degree of automation. Associations between motion parameters and age, sex, spinal level and disc degeneration were then assessed.

resultsThe median range of motion was 6.6° (range 0.1-28.9°). Associations between range of motion and age as well as spinal level, but not sex, were found. Disc degeneration determined a consistent reduction in the range of motion. The centre of rotation was most commonly located at the centre of the lower endplate or slightly lower. With progressive degeneration, centres of rotation were increasingly dispersed with no preferential directions.

conclusionThis study constitutes the largest analysis of the in vivo lumbar motion currently available and covers a wide range of clinical scenarios in terms of age and degeneration. Findings confirmed that ageing determines a reduction in the mobility independently of degeneration and that in degenerative levels, centres of rotation are dispersed around the centre of the intervertebral space.

Indexed as

Awards and PrizesIntervertebral Disc DegenerationLow Back PainBig DataBioengineeringBiomechanical PhenomenaHumansLumbar VertebraeRange of Motion, ArticularCentre of rotationFlexion–extensionImage registrationInstabilityRange of motion

Identifiers

PMID33475843

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.