Evidence map›Paper›PMID 33475441›Full record

ReviewExpert opinion on therapeutic patents2021

SARS-CoV-2 RNA-dependent RNA polymerase as a therapeutic target for COVID-19.

Ilaria Vicenti, Maurizio Zazzi, Francesco Saladini

Open access · greenAbstract readReview
In one paragraph

Review in Expert opinion on therapeutic patents, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 2 syntheses or guidelines pooled it, 120 citations in OpenAlex.

  1. Pooled it
  2. Characteristics of published/registered clinical trials on COVID-19 treatment: A systematic review.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2021
    Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. RedefiningMolecular therapy. Nucleic acids · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Small Molecule Drugs Targeting Viral Polymerases.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  16. Review
  17. Review
  18. Article
  19. A potential allosteric inhibitor of SARS-CoV-2 main protease (MFrontiers in molecular biosciences · 2024
    Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ilaria VicentiDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
Maurizio ZazziDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
Francesco SaladiniDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
University of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19 Drug TreatmentAdenosine MonophosphateAlanineAmidesAntiviral AgentsCytidineDrug DevelopmentDrug RepositioningHumansHydroxylaminesPyrazinesRNA-Dependent RNA PolymeraseSARS-CoV-2Adenosine MonophosphateAlanineAmidesAntiviral AgentsCytidinefavipiravirHydroxylaminesmolnupiravirPyrazinesremdesivirRNA-Dependent RNA PolymeraseCOVID-19drug repurposingnucleoside inhibitorsrna polymerasesars-CoV-2

Identifiers

PMID33475441
PMCPMC7938656
OpenAlexW3123629693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.