Evidence map›Paper›PMID 33475350›Full record

ArticleBioconjugate chemistry2021

ImmunoPET of CD146 in Orthotopic and Metastatic Breast Cancer Models.

Cuicui Li, Lei Kang, Kevin Fan, Carolina A Ferreira, Kaelyn V Becker, Nan Huo, Hanxiao Liu, Yunan Yang, Jonathan W Engle, Rongfu Wang and 3 more

Open access · greenAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Noninvasive ImmunoPET imaging of PD-L1 expression in non-small cell lung cancer and bladder cancer using [Colloids and surfaces. A, Physicochemical and engineering aspects · 2025
    Article
  5. ImmunoPET imaging of Trop2 expression in triple-negative breast cancer using [European journal of nuclear medicine and molecular imaging · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Theranostic role ofEuropean journal of nuclear medicine and molecular imaging · 2024
    Article
  11. Review
  12. Article
  13. Advances in PET/CT Imaging for Breast Cancer.Journal of clinical medicine · 2023
    Review
  14. Review
  15. Theranostic application ofEuropean journal of nuclear medicine and molecular imaging · 2022
    Article
  16. Observational
  17. European journal of nuclear medicine and molecular imaging · 2022
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Cuicui LiDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China 100034.
Lei KangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China 100034.
Kevin FanDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Carolina A FerreiraDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Kaelyn V BeckerDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Nan HuoDepartment of Medical Molecular Biology, Beijing Institute of Biotechnology, Beijing, China 100850.
Hanxiao LiuDepartment of Oncology, Harbin Medical University Affiliated Cancer Hospital, Harbin, China 150081.
Yunan YangDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Jonathan W EngleDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Rongfu WangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China 100034.
Xiaojie XuDepartment of Medical Molecular Biology, Beijing Institute of Biotechnology, Beijing, China 100850.
Dawei JiangDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.ORCID 0000-0002-4072-0075
Weibo CaiDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.ORCID 0000-0003-4641-0833
University of Wisconsin–Madison · USPeking University · CNHarbin Medical University · CNUnion Hospital · CN

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
NCI NIH HHS P30 CA014520
6 · The paper itself

Abstract

The overexpression of CD146 in breast cancer is considered a hallmark of tumor progression and metastasis, particularly in triple negative breast cancer. Aimed at imaging differential CD146 expressions in breast cancer, a noninvasive method for predictive prognosis and diagnosis was investigated using a

Indexed as

Neoplasm MetastasisAnimalsBreast NeoplasmsCD146 AntigenCell Line, TumorFemaleHumansMiceMice, Inbred BALB CMice, NudePositron-Emission TomographyPrognosisCD146 AntigenMCAM protein, human

Identifiers

PMID33475350
PMCPMC8292437
OpenAlexW3123175741

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.