Evidence map›Paper›PMID 33475227›Full record

ArticleJournal of applied clinical medical physics2021

Largely reduced OAR doses, and planning and delivery times for challenging robotic SBRT cases, obtained with a novel optimizer.

Marta K Giżyńska, Linda Rossi, Wilhelm den Toom, Maaike T W Milder, Kim C de Vries, Joost Nuyttens, Ben J M Heijmen

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Tightening the gradient: ten years of dosimetric refinement in head and neck reirradiation.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marta K GiżyńskaErasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Dr.Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Linda RossiErasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Dr.Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Wilhelm den ToomErasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Dr.Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Maaike T W MilderErasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Dr.Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Kim C de VriesErasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Dr.Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Joost NuyttensErasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Dr.Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Ben J M HeijmenErasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Dr.Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Erasmus MC Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, VOLO™ was introduced as a new optimizer for CyberKnife® planning. In this study, we investigated possibilities to improve treatment plans for MLC-based prostate SBRT with enhanced peripheral zone dose while sparing the urethra, and central lung tumors, compared to existing Sequential Optimization (SO). The primary focus was on reducing OAR doses. For 25 prostate and 25 lung patients treated with SO plans, replanning with VOLO™ was performed with the same planning constraints. For equal PTV coverage, almost all OAR plan parameters were improved with VOLO™. For prostate patients, mean rectum and bladder doses were reduced by 34.2% (P < 0.001) and 23.5% (P < 0.001), with reductions in D

Indexed as

RadiosurgeryRadiotherapy, Intensity-ModulatedRobotic Surgical ProceduresHumansMaleOrgans at RiskRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-AssistedCyberKnife SBRTsequential optimizertreatment planning for prostate and lungVOLO™

Identifiers

PMID33475227
PMCPMC7984474
OpenAlexW3124131332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.