Evidence map›Paper›PMID 33475162›Full record

ArticleJournal of medical virology2021

Epidemiology of cytomegalovirus Infection among mothers and infants in Colombia.

Angelica Rico, Sheila C Dollard, Diana Valencia, Sheryll Corchuelo, Van T Tong, Katherine Laiton-Donato, Minal M Amin, Monica Benavides, Phili Wong, Suzanne Newton and 14 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Angelica RicoInstituto Nacional de Salud, Bogota, Colombia.
Sheila C DollardNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0003-3969-9659
Diana ValenciaNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0002-9578-3751
Sheryll CorchueloInstituto Nacional de Salud, Bogota, Colombia.
Van T TongNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0002-3970-1440
Katherine Laiton-DonatoInstituto Nacional de Salud, Bogota, Colombia.
Minal M AminNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Monica BenavidesVysnova Partners, Inc., Landover, MD, USA.
Phili WongNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Suzanne NewtonEagle Global Scientific, Atlanta, Georgia, USA.
Marcela DazaVysnova Partners, Inc., Landover, MD, USA.
Jordan CatesNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Maritza GonzalezInstituto Nacional de Salud, Bogota, Colombia.ORCID 0000-0002-1516-3238
Laura D ZambranoNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Marcela M MercadoInstituto Nacional de Salud, Bogota, Colombia.
Elizabeth C AilesNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Helena M RodriguezInstituto Nacional de Salud, Bogota, Colombia.ORCID 0000-0003-3694-708X
Suzanne M GilboaNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Jacqueline AcostaVysnova Partners, Inc., Landover, MD, USA.ORCID 0000-0002-3864-7964
Jessica RicaldiNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Dioselina PelaezInstituto Nacional de Salud, Bogota, Colombia.
Margaret A HoneinNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0002-1523-7815
Martha L OspinaInstituto Nacional de Salud, Bogota, Colombia.ORCID 0000-0002-7484-9686
Tatiana M LanzieriNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0003-2499-4786

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

We assessed maternal and infant cytomegalovirus (CMV) infection in Colombia. Maternal serum was tested for CMV immunoglobulin G antibodies at a median of 10 (interquartile range: 8-12) weeks gestation (n = 1501). CMV DNA polymerase chain reaction was performed on infant urine to diagnose congenital (≤21 days of life) and postnatal (>21 days) infection. Maternal CMV seroprevalence was 98.1% (95% confidence interval [CI]: 97.5%-98.8%). Congenital CMV prevalence was 8.4 (95% CI: 3.9%-18.3%; 6/711) per 1000 live births. Among 472 infants without confirmed congenital CMV infection subsequently tested at age 6 months, 258 (54.7%, 95% CI: 50.2%-59.1%) had postnatal infection.

Indexed as

AdultAntibodies, ViralChild, PreschoolColombiaCytomegalovirusCytomegalovirus InfectionsDNA, ViralFemaleGestational AgeHumansImmunoglobulin GInfantMothersPregnancyPregnancy Complications, InfectiousSalivaAntibodies, ViralDNA, ViralImmunoglobulin GCMVColombiacongenital infectioncytomegalovirusnewbornspostnatal infectionprevalenceseroprevalence

Identifiers

PMID33475162
PMCPMC8292416

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.