ArticlePlant & cell physiology2021
A Novel Signaling Pathway Required for Arabidopsis Endodermal Root Organization Shapes the Rhizosphere Microbiome.
Article in Plant & cell physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Root colonization by beneficial rhizobacteria.FEMS microbiology reviews · 2024Pooled it
- The plant holobiont: integrating molecular priming and ecological legacies for climate-adaptive immunity.Essays in biochemistry · 2026Review
- Root cell wall plasticity in iron homeostasis: an overlooked frontier in plant nutrition.The New phytologist · 2026Review
- Arabidopsis root defense barriers support beneficial interactions with rhizobacterium Pseudomonas simiae WCS417.The New phytologist · 2025Article
- Towards Understanding the Factors Shaping the Composition and Function of theInternational journal of molecular sciences · 2025Review
- The root cortex of the Poaceae: a diverse, dynamic, and dispensable tissue.Plant and soil · 2025Review
- A Comparison of Rice Root Microbial Dynamics in Organic and Conventional Paddy Fields.Microorganisms · 2024Article
- Exploring the function of plant root diffusion barriers in sealing and shielding for environmental adaptation.Nature plants · 2024Review
- The Bacterial and Fungal Compositions in the Rhizosphere ofMicroorganisms · 2024Article
- Root phenotypes for improved nitrogen capture.Plant and soil · 2024Review
- Circadian regulation of metabolism across photosynthetic organisms.The Plant journal : for cell and molecular biology · 2023Review
- The Arabidopsis holobiont: a (re)source of insights to understand the amazing world of plant-microbe interactions.Environmental microbiome · 2023Review
- Spatially specific mechanisms and functions of the plant circadian clock.Plant physiology · 2022Review
- Root phenotypes as modulators of microbial microhabitats.Frontiers in plant science · 2022Review
- Uclacyanin Proteins Are Required for Lignified Nanodomain Formation within Casparian Strips.Current biology : CB · 2020Article
- Review
Corrections and comments
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Authors and funding
16 authors at 7 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Casparian strip (CS) constitutes a physical diffusion barrier to water and nutrients in plant roots, which is formed by the polar deposition of lignin polymer in the endodermis tissue. The precise pattern of lignin deposition is determined by the scaffolding activity of membrane-bound Casparian Strip domain proteins (CASPs), but little is known of the mechanism(s) directing this process. Here, we demonstrate that Endodermis-specific Receptor-like Kinase 1 (ERK1) and, to a lesser extent, ROP Binding Kinase1 (RBK1) are also involved in regulating CS formation, with the former playing an essential role in lignin deposition as well as in the localization of CASP1. We show that ERK1 is localized to the cytoplasm and nucleus of the endodermis and that together with the circadian clock regulator, Time for Coffee (TIC), forms part of a novel signaling pathway necessary for correct CS organization and suberization of the endodermis, with their single or combined loss of function resulting in altered root microbiome composition. In addition, we found that other mutants displaying defects in suberin deposition at the CS also display altered root exudates and microbiome composition. Thus, our work reveals a complex network of signaling factors operating within the root endodermis that establish both the CS diffusion barrier and influence the microbial composition of the rhizosphere.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.