Evidence map›Paper›PMID 33474904›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2021

[Diagnostic Application of Invasive Cardiopulmonary Exercise Test in Patients with Unexplained Dyspnea].

Zhuo-Lin Li, Yang-Ke He, Ya-Jie Xiang, Xin Yi, Zhong-Kai Zhu, Ai-Ling Li, Rui Xiang, Xiao-Li Han, Pu Wang, Wei Huang

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Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Zhuo-Lin LiDepartment of Cardiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Yang-Ke HeDepartment of Cardiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Ya-Jie XiangDepartment of Cardiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Xin YiDepartment of Cardiology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Zhong-Kai ZhuDepartment of Cardiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Ai-Ling LiDepartment of Cardiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Rui XiangDepartment of Cardiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Xiao-Li HanDepartment of Pneumology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Pu WangDepartment of Pneumology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Wei HuangDepartment of Cardiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
First Affiliated Hospital of Chongqing Medical University · CNChongqing Medical University · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the clinical diagnostic application of invasive cardiopulmonary exercise test (iCPET) in patients with unexplained dyspnea.

methodsA retrospective analysis was conducted, covering patients with a chief complaint of exertional dyspnea between May 5, 2017 and October 1, 2020. Right cardiac catheterization examination was performed on patients whose cause had not been identified through routine examination, and further iCPET was performed on patients if no clear etiology was identified through right cardiac catheterization. According to the results and the diagnostic criteria of iCPET, patients showing no obvious abnormalities in the right cardiac catheterization examination were divided into four subgroups: exercise-induced pulmonary arterial hypertension (eiPAH), exercise-induced heart failure with preserved ejection fraction (eiHFpEF), preload failure, and oxidative myopathy. By comparing the lab test, echocardiography, right heart catheter and iCPET peak exercise data of the subgroups, the disease distribution and exercise hemodynamic characteristics of patients with unexplained dyspnea examined by iCPET were described.

resultsOf the 1 046 patients with exertional dyspnea, 771 were diagnosed with routine examination, while among the remaining 275 patients, 131 (47.6%) were diagnosed with right cardiac catheterization and 144 (52.4%) showed no clear etiology after routine examination and right cardiac catheterization. Of these 144 patients, 49 (34.0%) received iCPET with a median exercise time of 375 s. A total of 47 patients completed the examination, with a male-to-female ratio of 0.27∶1 and an average age of (47.9±14.4) years old. Among the 47 patients, 76.6% (36/47) aged between 20 and 59 and 78.7% (36/47) lived in urban areas. The preload failure group (

Indexed as

Exercise TestHeart FailureAdultCardiac CatheterizationDyspneaExercise ToleranceFemaleHumansMaleMiddle AgedPulmonary Wedge PressureRetrospective StudiesExercise-induced heart failure with preserved ejection fractionExercise-induced pulmonary arterial hypertensionInvasive cardiopulmonary exercise testPreload failureUnexplained dyspnea

Identifiers

PMID33474904
PMCPMC10408953
OpenAlexW3124704765

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.