Evidence map›Paper›PMID 33474901›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2021

[Significance of Lipopolysaccharide Lipid A Gene Mutation of Extensively Drug-resistant

Hong-Bin Mao, Ming He, Su-Na He

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 71% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Hong-Bin MaoDepartment of Clinical Pharmacy, Kaifeng People's Hospital, Kaifeng 475000, China.
Ming HeDepartment of Clinical Pharmacy, the First Affiliated Hospital of Henan University, Kaifeng 475001, China.
Su-Na HeSchool of Medicine, Henan University of Science and Technology, Luoyang 471003, China.
First Affiliated Hospital of Henan University · CNHenan University of Science and Technology · CNKaifeng University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the significance of the resistance to polymyxin resistance of the extensively drug resistant

methodsIn the past two years, 72 XDRAB in the secretions of our patients were selected as the research object. According to the minimum inhibitory concentration (MIC) of the XDRAB strain on polymyxin, they were included in the drug resistance group and the sensitive group. The gene sequences of strains

resultsTentyone were in the drug resistant group, accounting for 21 (29.17%,) and 51 were in the sensitive group, accounting for 70.83%. Some strains had mutations in

conclusionXDRAB is resistant to polymyxin, which is related to mutations in LPS lipid A biosynthesis genes

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialDrug SynergismHumansLipid ALipopolysaccharidesMicrobial Sensitivity TestsMutationPolymyxinsAnti-Bacterial AgentsLipid ALipopolysaccharidesPolymyxinsAcinetobacter baumanniiDrug combinationDrug resistantGenetic mutationPolymyxin

Identifiers

PMID33474901
PMCPMC10408946
OpenAlexW3124091735

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.