Evidence map›Paper›PMID 33474708›Full record

ArticleAdvances in therapy2021

The Myth of Mild: Severe Exacerbations in Mild Asthma: An Underappreciated, but Preventable Problem.

Alan Kaplan

Open access · hybridAbstract read
In one paragraph

Article in Advances in therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Identifying and Addressing the Hidden Risks of Mild Asthma.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025
    Article
  3. High-flow nasal cannula in severe asthma exacerbations: current evidence and clinical perspectives.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  4. Asthma management in India: Changing paradigms.The Indian journal of medical research · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Alan KaplanDepartment of Family and Community Medicine, University of Toronto, Toronto, Canada. for4kids@gmail.com.ORCID http://orcid.org/0000-0001-8795-5528
University of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a common, chronic inflammatory airway disease, characterised by unpredictable episodes of worsening symptoms, or exacerbations. Causes of asthma exacerbations include viral infections, exposure to allergen and air pollution, all of which increase the underlying inflammation that typifies asthma. Most (50-75%) patients are classed as having mild asthma, with symptoms that can be readily controlled with available inhaled medications. Paradoxically, for the past 30 years, the first treatment recommended in asthma management guidelines was short-acting β

Indexed as

Anti-Asthmatic AgentsAsthmaAdministration, InhalationAdolescentAdrenal Cortex HormonesAdultBudesonide, Formoterol Fumarate Drug CombinationFormoterol FumarateHumansAdrenal Cortex HormonesAnti-Asthmatic AgentsBudesonide, Formoterol Fumarate Drug CombinationFormoterol FumarateAnti-inflammatory relieverICS/formoterolInflammationInhaled corticosteroidsMild asthmaSABA-relianceViral exacerbations

Identifiers

PMID33474708
PMCPMC7816833
OpenAlexW3122551350

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.