ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022
Quantifying microcalcification activity in the thoracic aorta.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04083118 (Non-invasive Detection of Bicuspid Aortic Valve-Related Thoracic Aortopathy), which is not on this map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Non-invasive Detection of Bicuspid Aortic Valve-Related Thoracic Aortopathy
Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- Effect of Denosumab or Alendronate on Vascular Calcification: Secondary Analysis of SALTIRE2 Randomized Controlled Trial.Journal of the American Heart Association · 2024Trial
- Vascular biomechanics and molecular disease activity in the thoracic aorta: a novel imaging method.European heart journal. Cardiovascular Imaging · 2022Trial
- Molecular Calcification Imaging and Ascending Aortic Disease in Patients With a Bicuspid Aortic Valve.JAMA network open · 2026Article
- Reproducibility ofCurrent cardiology reports · 2025Review
- Novel Quantification Protocol for Cardiovascular Calcification Progression Using Longitudinal MicroPET/MicroCT Images.Journal of visualized experiments : JoVE · 2024Article
- The Role of Positron Emission Tomography in Advancing the Understanding of the Pathogenesis of Heart and Vascular Diseases.Diagnostics (Basel, Switzerland) · 2023Review
- Magnetic Resonance Imaging and Computed Tomography for the Noninvasive Assessment of Arterial Aging: A Review by the VascAgeNet COST Action.Journal of the American Heart Association · 2023Review
- AorticJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- NaF-PET Imaging of Atherosclerosis Burden.Journal of imaging · 2023Review
- Artificial intelligence-based quantification of cardiac 18F-sodium fluoride uptake.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Thoracic AorticJACC. Cardiovascular imaging · 2022Observational
- Quantifying sodium [EJNMMI research · 2022Article
- A vessel of progress: Aortic microcalcification activity for the quantification ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Comment on: A novel model to assess disease activity in Takayasu arteritis based on 18F-FDG PET/CT: a Chinese cohort study.Rheumatology (Oxford, England) · 2022Article
- Advanced imaging tools for evaluating cardiac morphological and functional impairment in hypertensive disease.Journal of hypertension · 2022Review
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Authors and funding
18 authors at 7 institutions in 5 countries.
Funding
Abstract
backgroundStandard methods for quantifying positron emission tomography (PET) uptake in the aorta are time consuming and may not reflect overall vessel activity. We describe aortic microcalcification activity (AMA), a novel method for quantifying
methodsTwenty patients underwent two hybrid
resultsAortic microcalcification activity demonstrated excellent intra-observer (intraclass correlation coefficient 0.98) and inter-observer (intraclass correlation coefficient 0.97) repeatability with very good scan-rescan reproducibility (intraclass correlation coefficient 0.86) which were similar to previously described TBRmean and TBRmax methods. AMA analysis was much quicker to perform than standard TBR assessment (3.4min versus 15.1min, P<0.0001). AMA was correlated with Framingham stroke risk scores and Framingham risk score for hard cononary heart disease.
conclusionsAMA is a simple, rapid and reproducible method of quantifying global
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.