Evidence map›Paper›PMID 33474671›Full record

Observational studyDrugs & aging2021

Persistence of Effect of Medication Review on Potentially Inappropriate Prescriptions in Older Patients Following Hospital Discharge.

Camille Debacq, Julie Bourgueil, Amal Aidoud, Joëlle Bleuet, Marc Mennecart, Veronique Dardaine-Giraud, Bertrand Fougère

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Drugs & aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Observational
  5. Article
  6. Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Camille DebacqGériatrie, CHU de Tours, 2 Boulevard Tonnellé, 37000, Tours, France. camille.debacq@gmail.com.ORCID 0000-0002-1666-5475
Julie BourgueilPharmacie, CHU Tours, 2 Boulevard Tonnellé, 37000, Tours, France.
Amal AidoudGériatrie, CHU de Tours, 2 Boulevard Tonnellé, 37000, Tours, France.
Joëlle BleuetGériatrie, CHU de Tours, 2 Boulevard Tonnellé, 37000, Tours, France.
Marc MennecartGériatrie, CHU de Tours, 2 Boulevard Tonnellé, 37000, Tours, France.
Veronique Dardaine-GiraudGériatrie, CHU de Tours, 2 Boulevard Tonnellé, 37000, Tours, France.
Bertrand FougèreGériatrie, CHU de Tours, 2 Boulevard Tonnellé, 37000, Tours, France.
Centre Hospitalier Universitaire de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPotentially inappropriate prescriptions (PIPs) can lead to adverse drug reactions and should be avoided whenever possible.

objectiveOur objective was to assess the PIP resumption rate 6 months after discharge from our geriatric unit and to compare it with data in the literature.

methodsThis single-center observational study included patients aged ≥ 70 years with at least one PIP that had been stopped during hospitalization (according to Screening Tool for Older Persons Prescriptions [STOPP] and Screening Tool to Alert doctors to Right Treatment [START] criteria, version 2) between May 2018 and October 2018. We collected sociodemographic data, medication reconciliation data, and descriptive data during a comprehensive geriatric assessment. Each patient's medication history after discharge was determined in collaboration with their usual community pharmacist.

resultsA total of 125 patients (females 70%, mean age 87.1 years) were included. Data for the admission and discharge medication reconciliations were available for 44 patients (35%). On admission, 121 of the 125 patients (97%) were taking cardiovascular medication. Of the 336 treatments withdrawn, 61 (18.2%) had been re-prescribed at 6 months post-discharge-including half within the first month. The most frequent STOPP criterion was lack of indication (32%), and the overall PIP resumption rate was 22%. According to the anatomical therapeutic chemical (ATC) classification, the main organ system affected by PIPs was the cardiovascular system (47%, with a resumption rate of 17%).

conclusionOur results highlighted a low PIP resumption rate at 6 months and showed that a collaborative medication review is associated with persistent medium-term medication changes.

Indexed as

Inappropriate PrescribingPatient DischargeAftercareAgedAged, 80 and overFemaleHospitalsHumansMedication Reconciliation

Identifiers

PMID33474671
OpenAlexW3125985332

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.