Evidence map›Paper›PMID 33474609›Full record

ReviewArchives of microbiology2021

Phage therapy as strategy to face post-antibiotic era: a guide to beginners and experts.

Sabrina Royer, Aléxia Pinheiro Morais, Deivid William da Fonseca Batistão

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Mechanism ofMicroorganisms · 2026
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  10. Biologic and genomic characterization of a novel virulentFrontiers in veterinary science · 2024
    Article
  11. Article
  12. Bacteriophage therapy for drug-resistantFrontiers in cellular and infection microbiology · 2024
    Review
  13. Review
  14. Article
  15. Review
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  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sabrina RoyerLaboratory of Molecular Microbiology, Biomedical Science Institute, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil. sabrina.royer@ufu.br.ORCID http://orcid.org/0000-0002-2678-227X
Aléxia Pinheiro MoraisLaboratory of Molecular Microbiology, Biomedical Science Institute, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil.
Deivid William da Fonseca BatistãoSchool of Medicine, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interest in the therapeutic use of bacteriophages (phages) has emerged in recent years, driven mainly by the antimicrobial resistance crisis. This review aimed to summarize some important studies addressing the use of phages as a therapeutic alternative for multiresistant bacterial infections. To this end, a literature search was conducted to address the efficacy and versatility of phage therapy, the advantages and disadvantages of its use, and potential limitations for the application of phage therapy that need to be overcome, especially in Western countries. Thus, this review highlights that phage therapy may be a promising route in the treatment of infections caused by multidrug-resistant pathogens and that a combined approach has the potential to prolong the life of the current available antimicrobials. In addition, standardized clinical trials using monoclonal or polyclonal phages, alone or in combination with antimicrobials, are crucial to determine the real potential of these treatments in clinical practice.

Indexed as

Phage TherapyAnti-Bacterial AgentsBacteriaBacterial InfectionsBacteriophagesCombined Modality TherapyDrug Resistance, Multiple, BacterialHumansMicrobial InteractionsAnti-Bacterial AgentsBacteriophagesInfectionsMultidrug-resistant bacteriaPhage therapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.