Evidence map›Paper›PMID 33474580›Full record

ArticleEuropean journal of pediatrics2021

Demographic predictors of hospitalization and mortality in US children with COVID-19.

Alvaro Moreira, Kevin Chorath, Karthik Rajasekaran, Fiona Burmeister, Mubbasheer Ahmed, Axel Moreira

Open access · bronzeAbstract read
In one paragraph

Article in European journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.

  1. Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis.Journal of the Pediatric Infectious Diseases Society · 2024
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  11. Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis.medRxiv : the preprint server for health sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alvaro MoreiraDepartment of Pediatrics, University of Texas Health San Antonio, 7702 Floyd Curl Drive, San Antonio, TX, 78229, USA. MoreiraA@uthscsa.edu.ORCID http://orcid.org/0000-0003-3455-6608
Kevin ChorathUniversity of Pennsylvania, Philadelphia, PA, USA.
Karthik RajasekaranUniversity of Pennsylvania, Philadelphia, PA, USA.
Fiona BurmeisterDepartment of Pediatrics, University of Texas Health San Antonio, 7702 Floyd Curl Drive, San Antonio, TX, 78229, USA.
Mubbasheer AhmedBaylor College of Medicine, Houston, TX, USA.
Axel MoreiraBaylor College of Medicine, Houston, TX, USA.
The University of Texas Health Science Center at San Antonio · USUniversity of Pennsylvania · USBaylor College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding which children are at increased risk for poor outcome with COVID-19 is critical. In this study, we link pediatric population-based data from the US Center for Disease Control and Prevention to COVID-19 hospitalization and in-hospital death. In 27,045 US children with confirmed COVID-19, we demonstrate that African American [OR 2.28 (95% CI: 1.93, 2.70)] or mixed race [OR 2.95 (95% CI: 2.28, 3.82)] and an underlying medical condition [OR 3.55 (95% CI: 3.14, 4.01)] are strong predictors for hospitalization. Death occurred in 39 (0.19%) of 20,096 hospitalized children; children with a prior medical condition had an increased odd for death [OR 8.8 (95% CI: 3.7, 21.1)].Conclusion: Hospitalization and in-hospital death are rare in children diagnosed with COVID-19. However, children at higher risk for these outcomes include those with an underlying medical condition, as well as those of African American descent. What is Known: • Demographic factors are independent prognosticators of poor outcome in children with COVID-19. What is New: • Children with an underlying medical condition and those from an African American or mixed race/ethnicity are at high risk for COVID-19 hospitalization. • History of a comorbidity supersedes age, gender, and race/ethnicity as a risk factor for in-hospital pediatric COVID-19 death.

Indexed as

Hospital MortalityAdolescentChildChild, HospitalizedChild, PreschoolCOVID-19FemaleHospitalizationHumansInfantInfant, NewbornMaleUnited StatesYoung AdultChildrenCOVID-19COVID-NETPediatricSARS-CoV-2

Identifiers

PMID33474580
PMCPMC7817069
OpenAlexW3106682141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.