Evidence map›Paper›PMID 33474541›Full record

ArticleWorld journal of otorhinolaryngology - head and neck surgery2021

Laryngopharyngeal reflux disease, prevalence and clinical characteristics in ENT department of a tertiary hospital Tanzania.

Willybroad A Massawe, Aslam Nkya, Zefania Saitabau Abraham, Kassim M Babu, Ndeserua Moshi, Aveline A Kahinga, Daudi Ntunaguzi, Enica R Massawe

Open access · goldAbstract read
In one paragraph

Article in World journal of otorhinolaryngology - head and neck surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Global burden of Laryngopharyngeal reflux disease: a systematic review of epidemiology, cost-burden and awareness.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  2. Article
  3. Review
  4. Reducing the Duration of 24-Hour Multichannel Intraluminal Impedance-pH Monitoring for Laryngopharyngeal Reflux.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  5. Acid Assault: Unmasking the Toll of Laryngopharyngeal Reflux Disease on Vocal Health - A Literature Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  6. Usefulness of the Reflux Symptom Index and Reflux Finding Score in the Management of Laryngopharyngeal Reflux.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  7. Impact of Laryngopharyngeal Reflux in Patients with Voice Disorders.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  8. Effect of Laryngopharyngeal Reflux Disease on Middle Ear Function: A Case-Control Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
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  12. Laryngopharyngeal reflux induced sleep-related laryngospasm.Irish journal of medical science · 2023
    Article
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  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Willybroad A MassaweENT Department, Muhimbili National Hospital, Dar es Salaam, Tanzania.
Aslam NkyaENT Department, Muhimbili University of Health and Allied Science, Dar es Salaam, Tanzania.
Zefania Saitabau AbrahamDepartment of Surgery, University of Dodoma, College of Health and Allied Sciences, Tanzania.
Kassim M BabuENT Department, Muhimbili University of Health and Allied Science, Dar es Salaam, Tanzania.
Ndeserua MoshiENT Department, Muhimbili University of Health and Allied Science, Dar es Salaam, Tanzania.
Aveline A KahingaENT Department, Muhimbili University of Health and Allied Science, Dar es Salaam, Tanzania.
Daudi NtunaguziENT Department, Muhimbili University of Health and Allied Science, Dar es Salaam, Tanzania.
Enica R MassaweENT Department, Muhimbili University of Health and Allied Science, Dar es Salaam, Tanzania.
Muhimbili University of Health and Allied Sciences · TZMuhimbili National Hospital · TZThe University of Dodoma · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaryngopharyngeal reflux disease (LPRD) is a condition with nonspecific symptoms and most of times patients present late with advanced disease which may predispose to malignancy. The magnitude and clinical characteristics of this condition are not well known among patients attending Otorhinolaryngology services in Tanzania. MATERIALS AND

methodsThis was a hospital based descriptive cross sectional study, conducted in the wards and clinics of Otorhinolaryngology department of Muhimbili National Hospital. Patients with symptoms of Laryngopharyngeal reflux disease were included in the study. Data was collected using questionnaires and clinical examination forms, were processed and analysed by using SPSS. Results presented in frequency tables, cross tabulations and figures.

resultsThis study recruited 256 participants among them males were 131(51.2%).The mean age was (41.38 ± 13.94) years. Prevalence of Laryngopharyngeal reflux disease was 18.4% without gender predilection. The commonest symptoms were globus sensation, hoarseness of voice and excessive urge to clear the throat with 95.7%, 88.1% and 83.0% respectively while the most observed signs were thick endolaryngeal mucus, Vocal cord oedema and partial ventricular obliteration with 90.9%, 88.6% and 72.7% respectively. Lying down less than two hours after meal and spices foods consumption were the leading risk factors. Hypertension and Diabetes Mellitus type 2 were the most prevalent co morbid conditions associated with Laryngopharyngeal reflux disease.

conclusionThe prevalence of Laryngopharyngeal reflux disease is high among patients attending Otorhinolaryngology services at Muhimbili national hospital. All patients with Laryngopharyngeal reflux disease related symptoms should get thorough evaluation for early diagnosis and treatment.

Indexed as

Laryngopharyngeal reflux diseaseReflux finding scoreReflux scoring indexTertiary hospital

Identifiers

PMID33474541
PMCPMC7801257
OpenAlexW3080690838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.