Evidence map›Paper›PMID 33474538›Full record

ArticleWorld journal of otorhinolaryngology - head and neck surgery2021

Radiologic anatomy of the round window relevant to cochlear implantation and inner ear drug delivery.

Peter L Nguy, Sheela Saidha, Ann Jay, H Jeffrey Kim, Michael Hoa

Open access · goldAbstract read
In one paragraph

Article in World journal of otorhinolaryngology - head and neck surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Peter L NguyDepartment of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, Washington DC, USA.
Sheela SaidhaDepartment of Otolaryngology, University of Rochester Medical Center, Rochester, NY, USA.
Ann JayDepartment of Radiology, Georgetown University Medical Center, Washington DC, USA.
H Jeffrey KimDepartment of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, Washington DC, USA.
Michael HoaDepartment of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, Washington DC, USA.
Georgetown University · USGeorgetown University Medical Center · USUniversity of Rochester Medical Center · US

Funding

Cellular and Molecular Pathways for Hearing Restoration in the Adult Inner EarZIADC000088 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI HOA, MICHAEL · 2015 to 2025
$14.0M
6 · The paper itself

Abstract

objectiveTo determine anatomic relationships and variation of the round window membrane to bony surgical landmarks on computed tomography. STUDY

designRetrospective imaging review.

methods100 temporal bone images were evaluated. Direct measurements were obtained for membrane position. Vector distances and angulation from umbo and bony annulus were calculated from image viewer software coordinates.

resultsThe angle of round window membrane at junction with cochlear basal turn was (42.1 ± 8.6)°. The membrane's position relative to plane of the facial nerve through facial recess was (14.7 ± 5.2)° posterior from a reference line drawn through facial recess to carotid canal. Regarding transtympanic drug delivery, the round window membrane was directed 4.1 mm superiorly from the inferior annulus and 5.4 mm anteriorly from the posterior annulus. The round window membrane on average was angled superiorly from the inferior annulus (77.1 ± 27.9)° and slightly anteriorly from the posterior annulus (19.1 ± 11.1°). The mean distance of round window membrane from umbo was 4 mm and posteriorly rotated 30° clockwise from a perpendicular drawn from umbo to inferior annulus towards posterior annulus. Together, these measurements approximate the round window membrane in the tympanic membrane's posteroinferior quadrant.

conclusionsThese radiologic measurements demonstrate normal variations seen in round window anatomy relative to facial recess approach and bony tympanic annulus, providing a baseline to assess round window insertion for cochlear implantation and outlines anatomic factors affecting transtympanic drug delivery.

Indexed as

Cochlear implantationComputed tomographyRound windowTranstympanic drug delivery

Identifiers

PMID33474538
PMCPMC7801246
OpenAlexW3036567875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.