Evidence map›Paper›PMID 33473893›Full record

ArticleMitochondrial DNA. Part B, Resources2017

Mitochondrial heteroplasmy profiling in single human oocytes by next-generation sequencing.

Massimo Ancora, Massimiliano Orsini, Alessia Colosimo, Valentina Russo, Maurilia Marcacci, Maria De Santo, Marco D'Aurora, Liborio Stuppia, Valentina Gatta, Barbara Barboni and 2 more

Abstract read
In one paragraph

Article in Mitochondrial DNA. Part B, Resources, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Massimo AncoraIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale", Teramo, Italy.ORCID https://orcid.org/0000-0002-7121-6373
Massimiliano OrsiniIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale", Teramo, Italy.
Alessia ColosimoFacoltà di Bioscienze e tecnologie agro-alimentari e ambientali, Università degli Studi di Teramo, Teramo, Italy.
Valentina RussoFacoltà di Bioscienze e tecnologie agro-alimentari e ambientali, Università degli Studi di Teramo, Teramo, Italy.ORCID https://orcid.org/0000-0003-4368-2534
Maurilia MarcacciIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale", Teramo, Italy.
Maria De SantoCasa di Cura Privata Synergo Pierangeli, Spatocco, Chieti, Italy.
Marco D'AuroraDipartimento di Scienze Psicologiche, della Salute e del Territorio, Università "G. D'Annunzio" Chieti-Pescara, Chieti, Italy.
Liborio StuppiaDipartimento di Scienze Psicologiche, della Salute e del Territorio, Università "G. D'Annunzio" Chieti-Pescara, Chieti, Italy.
Valentina GattaDipartimento di Scienze Psicologiche, della Salute e del Territorio, Università "G. D'Annunzio" Chieti-Pescara, Chieti, Italy.
Barbara BarboniFacoltà di Bioscienze e tecnologie agro-alimentari e ambientali, Università degli Studi di Teramo, Teramo, Italy.
Cesare CammàIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale", Teramo, Italy.
Mauro MattioliIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale", Teramo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial DNA (mtDNA) plays a key role in the development of a competent oocyte. Mutations of the mitochondrial genome lead to an altered energetic metabolism with negative effects on oocyte developmental competence. In this study, mtDNA heteroplasmy at an intra-oocyte level and between the different analyzed human oocytes (

Indexed as

Heteroplasmic mutationshuman oocytemitochondrial DNAnext-generation sequencing

Identifiers

PMID33473893
PMCPMC7800564

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.