Evidence map›Paper›PMID 33473332›Full record

ArticleCurrent physical medicine and rehabilitation reports2020

New Developments in Non-invasive Brain Stimulation in Chronic Pain.

Timothy J Meeker, Rithvic Jupudi, Frederik A Lenz, Joel D Greenspan

Open access · greenAbstract read
In one paragraph

Article in Current physical medicine and rehabilitation reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Brain stimulation targets for chronic pain: Insights from meta-analysis, functional connectivity and literature review.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Pooled it
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  6. Review
  7. Review
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  10. Disentangling Diagnosis and Management of Fibromyalgia.Journal of rheumatic diseases · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Timothy J MeekerDept. of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA.
Rithvic JupudiDept. of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA.
Frederik A LenzDept. of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA.
Joel D GreenspanDept. of Neural and Pain Sciences, School of Dentistry, and Center to Advance Chronic Pain Research, Univ. of Maryland Baltimore, Baltimore, MD, USA.
Johns Hopkins University · USUniversity of Maryland, Baltimore · US

Funding

Human Networks for Behaviors related to the Expectation of PainR01NS109298 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LENZ, FRED · 2019 to 2023
$3.1M
Behaviors related to Human Neural Activity during Experimental Vigilance to PainR01NS107602 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LENZ, FRED · 2018 to 2022
$3.1M
NINDS NIH HHS R01 NS107602NINDS NIH HHS R01 NS109298
6 · The paper itself

Abstract

purpose of reviewThe goal of this review is to present a summary of the recent literature of a non-invasive brain stimulation (NIBS) to alleviate pain in people with chronic pain syndromes. This article reviews the current evidence for the use of transcranial direct current (tDCS) and repetitive transcranial magnetic stimulation (rTMS) to improve outcomes in chronic pain. Finally, we introduce the reader to novel stimulation methods that may improve therapeutic outcomes in chronic pain. RECENT

findingsWhile tDCS is approved for treatment of fibromyalgia in Canada and the European Union, no NIBS method is currently approved for chronic pain in the United States. Increasing sample sizes in randomized clinical trials (RCTs) seems the most efficient way to increase confidence in initial promising results. Trends at funding agencies reveal increased interest and support for NIBS such as recent Requests for Application from the National Institutes of Health. NIBS in conjunction with cognitive behavioral therapy and physical therapy may enhance outcomes in chronic pain. Novel stimulation methods, such as transcranial ultrasound stimulation, await rigorous study in chronic pain.

Indexed as

chronic painnon-invasive brain stimulationrepetitive transcranial magnetic stimulationrTMStDCStranscranial direct current stimulation

Identifiers

PMID33473332
PMCPMC7814313
OpenAlexW3024222887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.