Evidence map›Paper›PMID 33473276›Full record

ArticleFood science & nutrition2021

lncRNA HOTAIR knockdown suppresses gastric cancer cell biological activities.

Pan Chao, Feng Yongheng, Zhou Jin, Zhu Yu, Yang Shiyong, Yang Kunxing, Ma Yong

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pan ChaoDepartment of General Surgery Nanjing First Hospital Nanjing Medical University Nanjing China.
Feng YonghengDepartment of General Surgery Nanjing First Hospital Nanjing Medical University Nanjing China.
Zhou JinDepartment of General Surgery Nanjing First Hospital Nanjing Medical University Nanjing China.
Zhu YuDepartment of General Surgery Nanjing First Hospital Nanjing Medical University Nanjing China.
Yang ShiyongDepartment of General Surgery Nanjing First Hospital Nanjing Medical University Nanjing China.
Yang KunxingDepartment of General Surgery Nanjing First Hospital Nanjing Medical University Nanjing China.
Ma YongDepartment of General Surgery Nanjing First Hospital Nanjing Medical University Nanjing China.ORCID https://orcid.org/0000-0001-8090-623X
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to characterize the involvement of long noncoding RNA HOTAIR in gastric cancer development. Measurement of HOTAIR and miRNA-206 expression by in situ hybridization (ISH) and analyzed for the correlation between HOTAIR and miRNA-206 in gastric cancer tissues. To evaluate the effects of HOTAIR in gastric cancer, MTT assay, flow cytometry, transwell, and wound healing assays were applied. To explain the mechanism behind HOTAIR's involvement, the expression of proteins related to it was also measured by Western blotting. Finally, correlations among related factors were determined by a luciferase target experiment. HOTAIR expression significantly increased, and miRNA-206 expression significantly decreased in cancer tissues (

Indexed as

CCND1CCND2gastric cancerHOTAIRmiRNA‐206

Identifiers

PMID33473276
PMCPMC7802579
OpenAlexW3096994064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.