Evidence map›Paper›PMID 33473254›Full record

ArticleOncotarget2020

MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer.

Divya Bhagirath, Thao Ly Yang, Theresa Akoto, Nikhil Patel, Laura Z Tabatabai, Sharanjot Saini

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Divya BhagirathDepartment of Biochemistry and Molecular Biology, Augusta University, Augusta, GA, USA.
Thao Ly YangVeterans Affairs Medical Center, University of California, San Francisco, CA, USA.
Theresa AkotoDepartment of Cellular Biology and Anatomy, Augusta University, Augusta, GA, USA.
Nikhil PatelDepartment of Pathology, Augusta University, Augusta, GA, USA.
Laura Z TabatabaiVeterans Affairs Medical Center, University of California, San Francisco, CA, USA.
Sharanjot SainiDepartment of Biochemistry and Molecular Biology, Augusta University, Augusta, GA, USA.

Funding

MicroRNAs in frequently deleted loci regulate prostate cancer EMT and metastasisR01CA177984 · NCI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI SAINI, SHARANJOT · 2014 to 2018
$1.9M
NCI NIH HHS R01 CA177984
6 · The paper itself

Abstract

Prostate cancer (PCa) is a significant cause of male morbidity in the United States. Despite recent advances in diagnosis and therapeutic interventions, significant fraction of cases still progress to an advanced stage. Various genetic/epigenetic elements that facilitate this progression are not yet completely known and the mechanism that favors advanced disease is an area of investigation. A characteristic feature associated with progressive disease is deletion of chromosome 8p (chr8p) region, that harbors tumor-suppressor

Indexed as

chromosome 8pEMTmiR-4287prostate cancerSLUG

Identifiers

PMID33473254
PMCPMC7771715

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.