Evidence map›Paper›PMID 33473014›Full record

ArticleAsian journal of andrology

Viral infections and implications for male reproductive health.

Thiago A Teixeira, Yasmin C Oliveira, Felipe S Bernardes, Esper G Kallas, Amaro N Duarte-Neto, Sandro C Esteves, Joël R Drevet, Jorge Hallak

Open access · goldAbstract read
In one paragraph

Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Role of Seminal Exosomes in Reproduction.Journal of cellular physiology · 2025
    Review
  5. Article
  6. Review
  7. Effect of SARS-CoV-2 infection on sperm telomere length.Journal of assisted reproduction and genetics · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Male infertility.Nature reviews. Disease primers · 2023
    Review
  17. Identification ofTranslational andrology and urology · 2023
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Thiago A TeixeiraAndroscience, Science and Innovation Center in Andrology and High-Complex Clinical and Research Andrology Laboratory, São Paulo 04534-011, SP, Brazil.
Yasmin C OliveiraAndroscience, Science and Innovation Center in Andrology and High-Complex Clinical and Research Andrology Laboratory, São Paulo 04534-011, SP, Brazil.
Felipe S BernardesAndroscience, Science and Innovation Center in Andrology and High-Complex Clinical and Research Andrology Laboratory, São Paulo 04534-011, SP, Brazil.
Esper G KallasDepartment of Infectious and Parasitic Diseases, University of São Paulo, São Paulo 05403-000, SP, Brazil.
Amaro N Duarte-NetoBIAS - Brazilian Image Autopsy Study Group, Department of Pathology, University of São Paulo, São Paulo 05403-000, SP, Brazil.
Sandro C EstevesANDROFERT, Andrology and Human Reproduction Clinic, Campinas 13075-460, SP, Brazil.
Joël R DrevetGReD Institute, CNRS-INSERM-Université Clermont Auvergne, Faculty of Medicine, Clermont-Ferrand 63000, France.
Jorge HallakAndroscience, Science and Innovation Center in Andrology and High-Complex Clinical and Research Andrology Laboratory, São Paulo 04534-011, SP, Brazil.
AndroScience (United States) · USUniversidade de São Paulo · BRInserm · FRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal do Amapá · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral infections have haunted humankind since times immemorial. Overpopulation, globalization, and extensive deforestation have created an ideal environment for a viral spread with unknown and multiple shedding routes. Many viruses can infect the male reproductive tract, with potential adverse consequences to male reproductive health, including infertility and cancer. Moreover, some genital tract viral infections can be sexually transmitted, potentially impacting the resulting offspring's health. We have summarized the evidence concerning the presence and adverse effects of the relevant viruses on the reproductive tract (mumps virus, human immunodeficiency virus, herpes virus, human papillomavirus, hepatitis B and C viruses, Ebola virus, Zika virus, influenza virus, and coronaviruses), their routes of infection, target organs and cells, prevalence and pattern of virus shedding in semen, as well as diagnosis/testing and treatment strategies. The pathophysiological understanding in the male genital tract is essential to assess its clinical impact on male reproductive health and guide future research.

Indexed as

Hepatitis BHepatitis CHerpes GenitalisHumansMalePapillomavirus InfectionsReproductive HealthVirus DiseasesZika Virus Infectionmale genital tractreproductionsemensexual transmissionspermtestisviral persistenceviruses

Identifiers

PMID33473014
PMCPMC8269834
OpenAlexW3122913136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.