ReviewEuropean respiratory review : an official journal of the European Respiratory Society2021
Post-intubation subglottic stenosis: aetiology at the cellular and molecular level.
Review in European respiratory review : an official journal of the European Respiratory Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Efficacy and safety of serial intralesional corticosteroids for subglottic stenosis: systematic review & meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Pooled it
- Long-Term Outcomes of Patients Undergoing Cricothyrotomy at a Tertiary Care Level One Trauma Center.The Laryngoscope · 2026Article
- Exploring pathogenetic mechanisms in subglottic stenosis: A narrative review toward an integrated molecular classification.Multidisciplinary respiratory medicine · 2026Article
- Evaluation and Comparison of Treatment with Polymerised Collagen or Pirfenidone as Stand-Alone Therapy on the Production of Profibrotic Factors in Tracheal Stenosis and Tracheal Anastomosis Scarring After Resection.International journal of molecular sciences · 2026Article
- Cross-field airway management for distal postintubation stenosis: a case of successful reconstruction without ECMO support.Journal of cardiothoracic surgery · 2026Article
- Tilorone suppresses TGF-β-driven fibroblast activation and restores BMP-Smad1/5/8 signaling: implications for laryngotracheal fibrosis.Journal of translational medicine · 2026Article
- Factors Associated with Severity of Post-Intubation Cicatricial Laryngeal Stenosis in Children: A Retrospective Study.Journal of clinical medicine · 2026Article
- Intubated COVID-19 Patients More Likely to Develop Subglottic Stenosis.Laryngoscope investigative otolaryngology · 2026Article
- Mechanism of SLC15A3 Regulating Macrophage Oxidative Stress in the Pathogenesis of Traumatic Tracheal Stenosis.Journal of inflammation research · 2026Article
- Cricotracheal Resection for Subglottic Stenosis following Prior Dissection and Tracheostomy.Surgical case reports · 2026Article
- Acquired subglottic stenosis in children younger than 1 year in a resource-restricted hospital in South Africa.African journal of thoracic and critical care medicine · 2026Article
- Infraglottic Edema and Subglottic Stenosis in Tracheostomy-Dependent Children: A Retrospective Cohort Study.Laryngoscope investigative otolaryngology · 2025Article
- Association between anxiety and depression and sleep quality in benign laryngotracheal stenosis patients and analysis of risk factors.World journal of psychiatry · 2025Article
- Article
- Aerodigestive Approach in Evaluating Pediatric Patients With Recurrent Croup.The Annals of otology, rhinology, and laryngology · 2025Article
- Review
- Azithromycin Prevents Subglottic Stenosis in Mice.The Laryngoscope · 2025Article
- Subglottic Stenosis After Double-Lumen Tube Intubation With Reintubation: A Case Report and Review of Japanese Cases.Clinical case reports · 2025Article
- Proteomic Analysis of Surgery-induced Stress Post-Tracheal Transplantation Highlights Changes in Matrisome.The Laryngoscope · 2024Article
- The safety and effectiveness of the treatment of refractory post-intubation subglottic stenosis using short bronchial Dumon stent: a pilot study.Journal of thoracic disease · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subglottic stenosis (SGS) is a narrowing of the airway just below the vocal cords. This narrowing typically consists of fibrotic scar tissue, which may be due to a variety of diseases. This review focuses on post-intubation (PI) SGS. SGS can result in partial or complete narrowing of the airway. This narrowing is caused by fibrosis and can cause serious breathing difficulties. It can occur in both adults and children. The pathogenesis of post-intubation SGS is not well understood; however, it is considered to be the product of an abnormal healing process. This review discusses how intubation can change the local micro-environment, leading to dysregulated tissue repair. We discuss how mucosal inflammation, local hypoxia and biomechanical stress associated with intubation can promote excess tissue deposition that occurs during the pathological process of SGS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.