ArticleParasites & vectors2021
Predicting the impact of outdoor vector control interventions on malaria transmission intensity from semi-field studies.
Article in Parasites & vectors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Volatile pyrethroid spatial repellents for preventing mosquito bites: a systematic review and meta-analysis.EBioMedicine · 2025Pooled it
- Optimizing malaria vector control in the Greater Mekong Subregion: a systematic review and mathematical modelling study to identify desirable intervention characteristics.Parasites & vectors · 2024Pooled it
- A randomized, double-blind placebo-control study assessing the protective efficacy of an odour-based 'push-pull' malaria vector control strategy in reducing human-vector contact.Scientific reports · 2023Trial
- Trial
- Anopheles vector distribution and malaria transmission dynamics in Gbêkê region, central Côte d'Ivoire.Malaria journal · 2023Trial
- Estimating mosquito bionomics parameters with a hierarchical Bayesian model.Current research in parasitology & vector-borne diseases · 2026Article
- Cascades of effectiveness of next-generation insecticide-treated nets against malaria, from entomological trials to real-life conditions.Nature communications · 2025Article
- The effect of eave and window modifications on house entry behavior of Anopheles gambiae.Parasites & vectors · 2025Article
- Identifying gaps in protection from malaria vector biting in rural Cambodia using an entomological assessment and human behaviour observations.Malaria journal · 2025Article
- The effect of novel mosquito bite prevention tools on Anopheles minimus landing and key secondary endpoints: semi-field evaluations in Thailand.Malaria journal · 2024Article
- A unique mechanism of transfluthrin action revealed by mapping its binding sites in the mosquito sodium channel.Insect biochemistry and molecular biology · 2024Article
- Repelling Aedes aegypti mosquitoes with electric fields using insulated conductor wires.PLoS neglected tropical diseases · 2024Article
- Modelling the Influence of Climate and Vector Control Interventions on Arbovirus Transmission.Viruses · 2024Article
- Field evaluation of a volatile pyrethroid spatial repellent and etofenprox treated clothing for outdoor protection against forest malaria vectors in Cambodia.Scientific reports · 2024Article
- Evaluating human landing catches as a measure of mosquito biting and the importance of considering additional modes of action.Scientific reports · 2024Article
- Occupational exposure to malaria, leishmaniasis and arbovirus vectors in endemic regions: A systematic review.Current research in parasitology & vector-borne diseases · 2024Review
- CDC light traps underestimate the protective efficacy of an indoor spatial repellent against bites from wild Anopheles arabiensis mosquitoes in Tanzania.Malaria journal · 2023Article
- Human landing catches provide a useful measure of protective efficacy for the evaluation of volatile pyrethroid spatial repellents.Parasites & vectors · 2023Article
- Article
- Less is more: repellent-treated fabric strips as a substitute for full screening of open eave gaps for indoor and outdoor protection from malaria mosquito bites.Parasites & vectors · 2022Article
Corrections and comments
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Authors and funding
11 authors at 7 institutions in 6 countries.
Funding
Abstract
backgroundSemi-field experiments with human landing catch (HLC) measure as the outcome are an important step in the development of novel vector control interventions against outdoor transmission of malaria since they provide good estimates of personal protection. However, it is often infeasible to determine whether the reduction in HLC counts is due to mosquito mortality or repellency, especially considering that spatial repellents based on volatile pyrethroids might induce both. Due to the vastly different impact of repellency and mortality on transmission, the community-level impact of spatial repellents can not be estimated from such semi-field experiments.
methodsWe present a new stochastic model that is able to estimate for any product inhibiting outdoor biting, its repelling effect versus its killing and disarming (preventing host-seeking until the next night) effects, based only on time-stratified HLC data from controlled semi-field experiments. For parameter inference, a Bayesian hierarchical model is used to account for nightly variation of semi-field experimental conditions. We estimate the impact of the products on the vectorial capacity of the given Anopheles species using an existing mathematical model. With this methodology, we analysed data from recent semi-field studies in Kenya and Tanzania on the impact of transfluthrin-treated eave ribbons, the odour-baited Suna trap and their combination (push-pull system) on HLC of Anopheles arabiensis in the peridomestic area.
resultsComplementing previous analyses of personal protection, we found that the transfluthrin-treated eave ribbons act mainly by killing or disarming mosquitoes. Depending on the actual ratio of disarming versus killing, the vectorial capacity of An. arabiensis is reduced by 41 to 96% at 70% coverage with the transfluthrin-treated eave ribbons and by 38 to 82% at the same coverage with the push-pull system, under the assumption of a similar impact on biting indoors compared to outdoors.
conclusionsThe results of this analysis of semi-field data suggest that transfluthrin-treated eave ribbons are a promising tool against malaria transmission by An. arabiensis in the peridomestic area, since they provide both personal and community protection. Our modelling framework can estimate the community-level impact of any tool intervening during the mosquito host-seeking state using data from only semi-field experiments with time-stratified HLC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.