ArticleMalaria journal2021
Choosing interventions to eliminate forest malaria: preliminary results of two operational research studies inside Cambodian forests.
Article in Malaria journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 37 citations in OpenAlex.
- Identifying gaps in protection from malaria vector biting in rural Cambodia using an entomological assessment and human behaviour observations.Malaria journal · 2025Article
- Asymptomatic malaria infections and associated risk factors in malaria-eliminating settings of Nong District, Savannakhet Province, Lao People's Democratic Republic.Tropical medicine and health · 2025Article
- Anopheles mosquitoes in Mondulkiri forest, Cambodia: abundance, distribution, seasonal patterns and Plasmodium prevalence.Malaria journal · 2025Article
- News from the forest of Mondulkiri: additions to the mosquito fauna of Cambodia (Diptera: Culicidae).Parasite (Paris, France) · 2025Article
- Willingness to pay for a mosquito bite prevention 'forest pack' in Cambodia: results of a discrete choice experiment.Malaria journal · 2024Article
- Field evaluation of a volatile pyrethroid spatial repellent and etofenprox treated clothing for outdoor protection against forest malaria vectors in Cambodia.Scientific reports · 2024Article
- Intermittent preventive treatment for forest goers by forest malaria workers: an observational study on a key intervention for malaria elimination in Cambodia.The Lancet regional health. Western Pacific · 2024Article
- Progress towards malaria elimination in the Greater Mekong Subregion: perspectives from the World Health Organization.Malaria journal · 2024Article
- Using serological diagnostics to characterize remaining high-incidence pockets of malaria in forest-fringe Cambodia.Malaria journal · 2024Article
- Behavioural determinants of malaria risk, prevention, and care-seeking behaviours among forest-goers in Cambodia.Malaria journal · 2022Article
- Effect of out-of-village working activities on recent malaria exposure in the Peruvian Amazon using parametric g-formula.Scientific reports · 2022Article
- Accelerating malaria elimination in Cambodia: an intensified approach for targeting at-risk populations.Malaria journal · 2022Article
- Forest malaria and prospects for anti-malarial chemoprophylaxis among forest goers: findings from a qualitative study in Thailand.Malaria journal · 2022Article
- Forest malaria and prospects for anti-malarial chemoprophylaxis among forest goers: findings from a qualitative study in Lao PDR.Malaria journal · 2022Article
- Seroepidemiological surveillance, community perceptions and associated risk factors of malaria exposure among forest-goers in Northeastern Thailand.Frontiers in cellular and infection microbiology · 2022Article
- Acceptability and feasibility of malaria prophylaxis for forest goers: findings from a qualitative study in Cambodia.Malaria journal · 2021Article
- Clustering of malaria in households in the Greater Mekong Subregion: operational implications for reactive case detection.Malaria journal · 2021Article
- Forest malaria: the prevailing obstacle for malaria control and elimination in India.BMJ global health · 2021Review
- Eliminating Plasmodium falciparum malaria: results from tailoring active case detection approaches to remote populations in forested border areas in north-eastern Cambodia.Malaria journal · 2021Article
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Authors and funding
16 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundRapid elimination of Plasmodium falciparum malaria in Cambodia is a goal with both national and international significance. Transmission of malaria in Cambodia is limited to forest environments, and the main population at risk consists of forest-goers who rely on forest products for income or sustenance. The ideal interventions to eliminate malaria from this population are unknown.
methodsIn two forested regions of Cambodia, forest-goers were trained to become forest malaria workers (FMWs). In one region, FMWs performed mass screening and treatment, focal screening and treatment, and passive case detection inside the forest. In the other region, FMWs played an observational role for the first year, to inform the choice of intervention for the second year. In both forests, FMWs collected blood samples and questionnaire data from all forest-goers they encountered. Mosquito collections were performed in each forest.
resultsMalaria prevalence by PCR was high in the forest, with 2.3-5.0% positive for P. falciparum and 14.6-25.0% positive for Plasmodium vivax among forest-goers in each study site. In vectors, malaria prevalence ranged from 2.1% to 9.6%, but no P. falciparum was observed. Results showed poor performance of mass screening and treatment, with sensitivity of rapid diagnostic tests equal to 9.1% (95% CI 1.1%, 29.2%) for P. falciparum and 4.4% (95% CI 1.6%, 9.2%) for P. vivax. Malaria infections were observed in all demographics and throughout the studied forests, with no clear risk factors emerging.
conclusionsMalaria prevalence remains high among Cambodian forest-goers, but performance of rapid diagnostic tests is poor. More adapted strategies to this population, such as intermittent preventive treatment of forest goers, should be considered.
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