Evidence map›Paper›PMID 33472598›Full record

ArticleBMC cancer2021

The diagnostic value of lower glucose consumption for IDH1 mutated gliomas on FDG-PET.

Feng-Min Liu, Yu-Fei Gao, Yanyan Kong, Yihui Guan, Jinsen Zhang, Shuai-Hong Li, Dan Ye, Wenyu Wen, Chuantao Zuo, Wei Hua

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Feng-Min LiuDepartment of Neurosurgery, Huashan Hospital, Fudan University, 12 Middle Urumqi Road, Shanghai, 200040, China.
Yu-Fei GaoDepartment of Neurosurgery, China-Japan Union Hospital of Jilin University, Jilin Provincial Key Laboratory of Neuro-oncology, Changchun, Jilin, China.
Yanyan KongPET Center, Huashan Hospital, Fudan University, Shanghai, China.
Yihui GuanPET Center, Huashan Hospital, Fudan University, Shanghai, China.
Jinsen ZhangDepartment of Neurosurgery, Huashan Hospital, Fudan University, 12 Middle Urumqi Road, Shanghai, 200040, China.
Shuai-Hong LiDepartment of Neurology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.
Dan YeThe Molecular and Cell Biology Lab, Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Wenyu WenDepartment of Neurosurgery, Huashan Hospital, Fudan University, 12 Middle Urumqi Road, Shanghai, 200040, China.
Chuantao ZuoPET Center, Huashan Hospital, Fudan University, Shanghai, China.
Wei HuaDepartment of Neurosurgery, Huashan Hospital, Fudan University, 12 Middle Urumqi Road, Shanghai, 200040, China. hs_glioma@126.com.ORCID http://orcid.org/0000-0001-6409-5078
Fudan University · CNJilin University · CNShanghai Medical College of Fudan University · CN

Funding

Education Department of Jilin Province JJKH20190005KJFinancial Department of Jilin Province 2018SCZ030Join Breakthrough Project for New Frontier Technologies of Shanghai Hospital Development Center SHDC12016120Science and Technology of Jilin Province 20180101136JCShanghai science and technology commission 17430750200
6 · The paper itself

Abstract

backgroundNon-invasive diagnosis of IDH1 mutation for gliomas has great clinical significance, and PET has natural advantage to detect metabolism, as IDH mutated gliomas share lower glucose consumption.

methodsClinical data of patients with gliomas and

resultsSeventy-one glioma cases were enrolled, including 30 carrying IDH1 mutation. The sensitivity and specificity dependent on SUV

conclusionSUV

Indexed as

MutationBrain NeoplasmsCase-Control StudiesFluorodeoxyglucose F18Follow-Up StudiesGliomaGlucoseHumansIsocitrate DehydrogenasePositron-Emission TomographyPrognosisRadiopharmaceuticalsROC CurveTumor Cells, CulturedFluorodeoxyglucose F18GlucoseIDH1 protein, humanIsocitrate DehydrogenaseRadiopharmaceuticalsDiagnosisGliomaGlucoseIsocitrate dehydrogenase mutationPET

Identifiers

PMID33472598
PMCPMC7816361
OpenAlexW3122382160

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.