Evidence map›Paper›PMID 33472518›Full record

ArticleRNA biology2021

Intron-assisted, viroid-based production of insecticidal circular double-stranded RNA in

Beltrán Ortolá, Teresa Cordero, Xu Hu, José-Antonio Daròs

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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  7. Outlook on RNAi-Based Strategies for ControllingPathogens (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Beltrán OrtoláInstituto de Biología Molecular y Celular de Plantas (Consejo Superior de Investigaciones Científicas-Universitat Politècnica de Valencia), Valencia, Spain.ORCID 0000-0002-3144-1015
Teresa CorderoInstituto de Biología Molecular y Celular de Plantas (Consejo Superior de Investigaciones Científicas-Universitat Politècnica de Valencia), Valencia, Spain.
Xu HuCorteva Agriscience, Johnston, Iowa, USA.ORCID 0000-0002-1372-5399
José-Antonio DaròsInstituto de Biología Molecular y Celular de Plantas (Consejo Superior de Investigaciones Científicas-Universitat Politècnica de Valencia), Valencia, Spain.ORCID 0000-0002-6535-2889
Consejo Superior de Investigaciones Científicas · ESCorteva (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA interference (RNAi) is a natural mechanism for protecting against harmful genetic elements and regulating gene expression, which can be artificially triggered by the delivery of homologous double-stranded RNA (dsRNA). This mechanism can be exploited as a highly specific and environmentally friendly pest control strategy. To this aim, systems for producing large amounts of recombinant dsRNA are necessary. We describe a system to efficiently produce large amounts of circular dsRNA in

Indexed as

IntronsAnimalsColeopteraEscherichia coliInsecticidesInsect ProteinsPlant DiseasesRNA, Double-StrandedViroidsZea maysInsecticidesInsect ProteinsRNA, Double-StrandedDiabrotica virgiferadouble-stranded RNAeggplant latent viroidEscherichia coligroup-I self-splicing intronintron-exon permutationRNA interference

Identifiers

PMID33472518
PMCPMC8582998
OpenAlexW3125361945

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.