Evidence map›Paper›PMID 33472506›Full record

ReviewAdipocyte2021

The role and research progress of the balance and interaction between regulatory T cells and other immune cells in obesity with insulin resistance.

Leiling Liu, Jiahui Hu, Yating Wang, Hao Lei, Danyan Xu

Open access · goldAbstract readReview
In one paragraph

Review in Adipocyte, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Insulin Resistance and Inflammation.International journal of molecular sciences · 2026
    Review
  2. Intestinal CD4Molecular medicine reports · 2025
    Article
  3. Weight Loss-Associated Remodeling of Adipose Tissue Immunometabolism.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Leiling LiuDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University , Changsha, Hunan, China.
Jiahui HuDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University , Changsha, Hunan, China.
Yating WangDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University , Changsha, Hunan, China.
Hao LeiDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University , Changsha, Hunan, China.
Danyan XuDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University , Changsha, Hunan, China.
Central South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic homoeostasis in adipose tissue plays a major role in obesity-related insulin resistance (IR). Regulatory T (Treg) cells have been recorded to regulate metabolic homoeostasis in adipose tissue. However, their specific mechanism is not yet known. This review aims to present the role of Treg cells and other immune cells in obesity-associated IR, focusing on the balance of numbers and functions of Treg cells and other immune cells as well as the crucial role of their interactions in maintaining adipose tissue homoeostasis. Th1 cells, Th17 cells, CD8

Indexed as

Adipose TissueAnimalsCell DifferentiationHomeostasisHumansImmunity, InnateInflammationInsulin ResistanceLymphocytesMacrophagesNatural Killer T-CellsObesityTh17 CellsTh1 CellsT-Lymphocytes, Regulatoryadipose tissueinsulin resistance (IR)Obesityregulatory T (Treg) cells

Identifiers

PMID33472506
PMCPMC7834085
OpenAlexW3125955895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.