Evidence map›Paper›PMID 33472035›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2021

AAV Joins the Rank of Genotoxic Vectors.

Utpal P Davé, Kenneth Cornetta

Abstract readComment
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Structural basis of liver de-targeting and neuronal tropism of CNS-targeted AAV capsids.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  2. Review
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  14. Article
  15. Delivering AAV to the Central Nervous and Sensory Systems.Trends in pharmacological sciences · 2021
    Review
  16. Liver gene therapy and hepatocellular carcinoma: A complex web.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Utpal P DavéDivision of Hematology/Oncology, Department of Medicine, Indiana University School of Medicine, Walther Hall, 980 W. Walnut St., Rm. C312J, Indianapolis, IN 46202, USA.
Kenneth CornettaDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Walther Hall 980 W. Walnut Street, R3 C649, Indianapolis, IN 46202-5121, USA. Electronic address: kcornett@iu.edu.

Funding

The Role of LMO2 in the Pathogenesis of T-cell LeukemiaR01CA207530 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI DAVE, UTPAL P · 2016 to 2020
$1.8M
BLRD VA I01 BX001799NCI NIH HHS R01 CA207530
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leukodystrophy, Globoid CellDependovirusDNA DamageGenetic VectorsHumans

Identifiers

PMID33472035
PMCPMC7854348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.