Evidence map›Paper›PMID 33472033›Full record

ReviewMolecular therapy : the journal of the American Society of Gene Therapy2021

siRNA Drugs: Here to Stay.

John J Rossi, Daniel J Rossi

Abstract readReview
In one paragraph

Review in Molecular therapy : the journal of the American Society of Gene Therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Nucleic acid drugs: recent progress and future perspectives.Signal transduction and targeted therapy · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John J RossiDepartment Molecular and Cellular Biology, Beckman Research Institute, City of Hope, Duarte, CA, USA. Electronic address: jrossi@coh.org.
Daniel J RossiIstat Therapeutics, Inc., Duarte, CA, USA.

Funding

COMBINATORIAL USE OF CCR5 RIBOZYMES WITH ANTI HIV1 RNASR01AI042552 · NIAID · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI ROSSI, JOHN JOSEPH · 1998 to 2019
$7.8M
Develop novel inhaled neutralizing RNA therapeutics against COVID-19R21AI161075 · NIAID · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI ROSSI, JOHN JOSEPH · 2021 to 2021
$396k
NIAID NIH HHS R01 AI042552NIAID NIH HHS R21 AI161075
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic TherapyHumansRNA, Small InterferingRNA, Small Interfering

Identifiers

PMID33472033
PMCPMC7854346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.