ArticleHuman brain mapping2021
Structural connectivity of the human massa intermedia: A probabilistic tractography study.
Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Interthalamic adhesion alterations in multiple sclerosis: associations with thalamic damage and cognition.Journal of neurology · 2026Article
- Cognitive, neuroimaging, and genetic insights on the interthalamic adhesion from a large cohort study of 591 subjects.Scientific reports · 2025Article
- Article
- Exploring the impact of the interthalamic adhesion on human cognition: insights from healthy subjects and thalamic stroke patients.Journal of neurology · 2024Article
- Absence of the interthalamic adhesion (ITA) as a neuroanatomical association or risk factor for neuropsychiatric disorders: A systemic review and meta-analysis.Indian journal of psychiatry · 2023Review
- The Prevalence, Location, and Dimensions Of Interthalamic Adhesions and Their Clinical Significance: Corpse Brain Analysis.Asian journal of neurosurgery · 2022Article
- Massa intermedia of the thalamus: an anatomical study using magnetic resonance imaging.Surgical and radiologic anatomy : SRA · 2021Article
- Structural connectivity of the human massa intermedia: A probabilistic tractography study.Human brain mapping · 2021Article
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Authors and funding
5 authors.
Funding
Abstract
The role of massa intermedia (MI) is poorly understood in humans. Recent studies suggest its presence may play a role in normal human neurocognitive function while prior studies have shown the absence of MI correlated with psychiatric disorders. There is growing evidence that MI is likely a midline white matter conduit, responsible for interhemispheric connectivity, similar to other midline commissures. MI presence was identified in an unrelated sample using the Human Connectome Project database. MI structural connectivity maps were created and gray matter target regions were identified using probabilistic tractography of the whole brain. Probabilistic tractography revealed an extensive network of connections between MI and limbic, frontal and temporal lobes as well as insula and pericalcarine cortices. Women compared to men had stronger connectivity via their MI. The presented results support the role of MI as a midline commissure with strong connectivity to the amygdala, hippocampus, and entorhinal cortex.
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Registered trials
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