Evidence map›Paper›PMID 33471825›Full record

ArticlePloS one2021

Prevalence and sociodemographic correlates of anogenital Human Papillomavirus (HPV) carriage in a cross-sectional, multi-ethnic, community-based Asian male population.

Su Pei Khoo, Mohd Khairul Anwar Shafii, Nirmala Bhoo-Pathy, Siew Hwei Yap, Shridevi Subramaniam, Nazrila Hairizan Nasir, Zhang Lin, Jerome Belinson, Pik Pin Goh, Xinfeng Qu and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Prevalence of the most common types of high-risk HPV and p16Postepy dermatologii i alergologii · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Su Pei KhooFaculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Mohd Khairul Anwar ShafiiFaculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Nirmala Bhoo-PathyFaculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Siew Hwei YapFaculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Shridevi SubramaniamNational Clinical Research Centre, Ministry of Health, Putrajaya, Malaysia.
Nazrila Hairizan NasirDivision of Family Health Development, Ministry of Health, Putrajaya, Malaysia.
Zhang LinBeijing Genome Institute, Shen Zhen, China.
Jerome BelinsonPreventive Oncology International Inc and the Cleveland Clinic, Cleveland, Ohio, United States of America.
Pik Pin GohNational Clinical Research Centre, Ministry of Health, Putrajaya, Malaysia.
Xinfeng QuPreventive Oncology International Inc and the Cleveland Clinic, Cleveland, Ohio, United States of America.
Patti GravittDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Yin Ling WooFaculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0003-1742-1066
University of Malaya · MYMinistry of Health · MYCleveland Clinic · USChinese National Human Genome Center · CNUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAddressing the burden of HPV-associated diseases among men is increasingly becoming a public health issue. The main objective of this study was to determine HPV prevalence among a healthy community-based Malaysian men.

methodThis was a cross-sectional study that recruited 503 healthy males from 3 community-based clinics in Selangor, Malaysia. Genital and anal samples were collected from each participant for 14 high risk and 2 low risk HPV DNA detection and genotyping. All participants responded to a set of detailed sociodemographic and sexual behaviour questionnaire.

resultsThe median age at enrolment was 40 years old (IQR: 31-50). The anogenital HPV6/11 prevalence was 3.2% whereas high risk HPV prevalence was 27.1%. The genital HPV prevalence for HPV6/11 was 2.9% while high risk HPV was 18.8%. HPV6/11 prevalence in the anal canal was 1.6% and high risk HPV was 12.7%. HPV 18 was the most prevalent genotype detected in the anogenital area. There was a significant independent association between genital and anal HPV infections.

conclusionAnogenital HPV infection is common among Malaysian men. These findings emphasize the ubiquity of HPV infection and thus the value of population-wide access to HPV prevention.

Indexed as

AdolescentAdultAnal CanalEthnicityGenitalia, MaleHuman papillomavirus 11Human papillomavirus 6Human Papillomavirus DNA TestsHumansIndependent LivingMalaysiaMaleMiddle AgedPapillomavirus InfectionsPrevalenceSocioeconomic Factors

Identifiers

PMID33471825
PMCPMC7817061
OpenAlexW3122951669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.