SynthesisJournal of clinical gastroenterology2021
Efficacy and Safety of Full-thickness Resection Device (FTRD) for Colorectal Lesions Endoscopic Full-thickness Resection: A Systematic Review and Meta-Analysis.
Synthesis in Journal of clinical gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Efficacy and safety of salvage endoscopy in the treatment of residual or recurrent colorectal neoplasia after endoscopic resection: a systematic review and meta-analysis.Surgical endoscopy · 2024Pooled it
- Endoscopic full-thickness resection for upper gastrointestinal tract lesions: a systematic review and meta-analysis.Surgical endoscopy · 2023Pooled it
- Clinical Outcomes of Colorectal Endoscopic Full-Thickness Resection Using the Full-Thickness Resection Device: A Multicenter Study.DEN open · 2027Article
- Efficacy and safety of endoscopic transcecal appendectomy: a systematic review and meta-analysis.Translational gastroenterology and hepatology · 2026Article
- Cap-suction pseudopolyp formation during underwater mucosal resection for intra-appendiceal lesions.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2025Article
- Real-world topographical efficacy, procedural outcome and safety of endoscopic full thickness resection in colon segments.World journal of gastrointestinal endoscopy · 2025Article
- Development and validation of a model for predicting electrocoagulation syndrome after endoscopic full-thickness resection of gastric tumors.Surgical endoscopy · 2025Article
- Endoscopic Full Thickness Resection Device (FTRDDiagnostics (Basel, Switzerland) · 2025Review
- Endoscopic mucosal resection with an over-the-scope clip for colorectal tumors (with video).DEN open · 2025Article
- Histology of colonic submucosal lesions reveals a high proportion of benign lesions that do not require R0 en bloc endoscopic resection.Endoscopy international open · 2025Article
- Clinical safety of a novel over-the-scope gastroduodenal full-thickness resection device for the treatment of upper GI tract lesions: a multicenter experience.iGIE : innovation, investigation and insights · 2024Article
- Endoscopic approaches to the management of dysplasia in inflammatory bowel disease: A state-of-the-art narrative review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Review
- Transcecal endoscopic appendectomy for management of complex appendiceal polyps extending into the appendiceal orifice.Endoscopy international open · 2024Article
- Full-thickness resection device for management of lesions involving the appendiceal orifice: Systematic review and meta-analysis.Endoscopy international open · 2023Article
- Endoscopic full-thickness resection (eFTR) in colon and rectum: indications and outcomes in the first 37 cases in a single center.Surgical endoscopy · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND AND
aimsEndoscopic full-thickness resection (eFTR) is a field of increasing interest that offers a minimally invasive resection modality for lesions that are not amenable for resection by conventional methods. Full-thickness resection device (FTRD) is a new device that was developed for a single-step eFTR using an over-the scope-clip. In this meta-analysis, we aim to assess the efficacy and safety of FTRD for eFTR of colorectal lesions.
methodsA Comprehensive literature review of different databases to identify studies reporting FTRD with outcomes of interest was performed. Studies with <10 cases were excluded. Rates of histologic complete resection (R0), technical success, and complications were extracted. Efficacy was assessed by using the technical and the R0 rates whereas safety was assessed by using the complications rates. Weighted pooled rates (WPRs) and the 95% confidence interval (CI) were calculated depending on the heterogeneity (I2 statistics).
resultsNine studies including 551 patients with 555 lesions were included in this study. The WPR for overall R0 was 82.4% (95% CI: 79.0%-85.5%),with moderate heterogeneity (I2=34.8%). The WPR rate for technical success was 89.25% (95% CI: 86.4%-91.7%), with low heterogeneity (I2=23.7%). The WPR for total complications rate was 10.2% (7.8, 12.8%) with no heterogeneity. The pooled rate for minor bleeding, major bleeding, postpolypectomy syndrome, and perforation were 3.2%, 0.97%, 2.2%, and 1.2%, respectively. Of 44 periappendicular lesions, the pooled rate for acute appendicitis was 19.7%.
conclusionsFTRD seems to be effective and safe for eFTR of difficult colorectal lesions. Large prospective studies comparing FTRD with conventional resection techniques are warranted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.