Evidence map›Paper›PMID 33471195›Full record

ArticleSurgery today2021

The prognostic impact of peritoneal washing cytology for otherwise resectable extrahepatic cholangiocarcinoma patients.

Tatsuaki Sumiyoshi, Kenichiro Uemura, Naru Kondo, Kenjiro Okada, Shingo Seo, Hiroyuki Otsuka, Masahiro Serikawa, Yasutaka Ishii, Norimasa Kuraoka, Takuya Sakoda and 4 more

Abstract read
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In one paragraph

Article in Surgery today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tatsuaki SumiyoshiDepartment of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1 2 3 Kasumi, Minami ku, Hiroshima, 734 8551, Japan.
Kenichiro UemuraDepartment of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1 2 3 Kasumi, Minami ku, Hiroshima, 734 8551, Japan. umk@hiroshima-u.ac.jp.
Naru KondoDepartment of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1 2 3 Kasumi, Minami ku, Hiroshima, 734 8551, Japan.
Kenjiro OkadaDepartment of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1 2 3 Kasumi, Minami ku, Hiroshima, 734 8551, Japan.
Shingo SeoDepartment of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1 2 3 Kasumi, Minami ku, Hiroshima, 734 8551, Japan.
Hiroyuki OtsukaDepartment of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1 2 3 Kasumi, Minami ku, Hiroshima, 734 8551, Japan.
Masahiro SerikawaDepartment of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Science, Hiroshima University, Hiroshima, Japan.
Yasutaka IshiiDepartment of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Science, Hiroshima University, Hiroshima, Japan.
Norimasa KuraokaDepartment of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1 2 3 Kasumi, Minami ku, Hiroshima, 734 8551, Japan.
Takuya SakodaDepartment of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1 2 3 Kasumi, Minami ku, Hiroshima, 734 8551, Japan.
Kenta BabaDepartment of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1 2 3 Kasumi, Minami ku, Hiroshima, 734 8551, Japan.
Takumi HaradaDepartment of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1 2 3 Kasumi, Minami ku, Hiroshima, 734 8551, Japan.
Yoshiaki MurakamiDigestive Disease Center, Hiroshima Memorial Hospital, Hiroshima, Japan.
Shinya TakahashiDepartment of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1 2 3 Kasumi, Minami ku, Hiroshima, 734 8551, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical importance of peritoneal washing cytology (PWC) for cholangiocarcinoma patients remains unclear. The clinical data of 137 extrahepatic cholangiocarcinoma patients who received PWC and curative surgery were retrospectively analyzed. Among the 137 patients analyzed, five (3.6%) had positive PWC, and 132 (96.4%) had negative PWC. The median survival time in patients with negative PWC was 6.45 years, and the overall 1-, 2-, and 5-year survival rates were 86.5%, 75.3%, and 51.6%, respectively. The median survival time in patients with positive PWC was 2.56 years, and the overall 1-, 2-, and 5-year survival rates were 60.0%, 60.0%, and 40.0%, respectively. A multivariate analysis revealed that positive lymph node metastasis (P < 0.001), positive perineural invasion (P = 0.014) and no use of adjuvant chemotherapy (P < 0.001), but not positive PWC were independently associated with a worse overall survival. In conclusion, surgery and subsequent chemotherapy might be a therapeutic option for cholangiocarcinoma patients with positive PWC.

Indexed as

Peritoneal LavageAdolescentAdultAgedAged, 80 and overBile Duct NeoplasmsCholangiocarcinomaCytodiagnosisFemaleHumansLymphatic MetastasisMaleMiddle AgedPrognosisRetrospective StudiesSurvival RateExtrahepatic cholangiocarcinomaPeritoneal washing cytologySurgery

Identifiers

PMID33471195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.