Evidence map›Paper›PMID 33470354›Full record

ArticleRevista Brasileira de terapia intensiva

Mechanical ventilation withdrawal as a palliative procedure in a Brazilian intensive care unit.

Fábio Holanda Lacerda, Pedro Garcia Checoli, Carla Marchini Dias da Silva, Carlos Eduardo Brandão, Daniel Neves Forte, Bruno Adler Maccagnan Pinheiro Besen

Abstract read
In one paragraph

Article in Revista Brasileira de terapia intensiva. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Palliative extubation in intensive care units: scoping review.Revista da Escola de Enfermagem da U S P · 2026
    Article
  3. Article
  4. Article
  5. Palliative extubation experience in a community hospital in southern Brazil.Revista da Associacao Medica Brasileira (1992) · 2023
    Article
  6. Prevalence, Outcomes, and Risk Factors for Cardiorespiratory Arrest in the Intensive Care Unit: An Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fábio Holanda LacerdaUnidade de Terapia Intensiva, Hospital da Luz - São Paulo (SP), Brasil.ORCID http://orcid.org/0000-0001-6456-9413
Pedro Garcia ChecoliUnidade de Terapia Intensiva, Hospital da Luz - São Paulo (SP), Brasil.
Carla Marchini Dias da SilvaUnidade de Terapia Intensiva, Hospital da Luz - São Paulo (SP), Brasil.
Carlos Eduardo BrandãoUnidade de Terapia Intensiva, Hospital da Luz - São Paulo (SP), Brasil.
Daniel Neves FortePrograma de Cuidados Paliativos, Hospital Sírio-Libanês - São Paulo (SP), Brasil.
Bruno Adler Maccagnan Pinheiro BesenUnidade de Terapia Intensiva, Hospital da Luz - São Paulo (SP), Brasil.ORCID http://orcid.org/0000-0002-3516-9696

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the characteristics and outcomes of patients undergoing mechanical ventilation withdrawal and to compare them to mechanically ventilated patients with limitations (withhold or withdrawal) of life-sustaining therapies but who did not undergo mechanical ventilation withdrawal.

methodsThis was a retrospective cohort study from January 2014 to December 2018 of mechanically ventilated patients with any organ support limitation admitted to a single intensive care unit. We compared patients who underwent mechanical ventilation withdrawal and those who did not regarding intensive care unit and hospital mortality and length of stay in both an unadjusted analysis and a propensity score matched subsample. We also analyzed the time from mechanical ventilation withdrawal to death.

resultsOut of 282 patients with life-sustaining therapy limitations, 31 (11%) underwent mechanical ventilation withdrawal. There was no baseline difference between groups. Intensive care unit and hospital mortality rates were 71% versus 57% and 93% versus 80%, respectively, among patients who underwent mechanical ventilation withdrawal and those who did not. The median intensive care unit length of stay was 7 versus 8 days (p = 0.6), and the hospital length of stay was 9 versus 15 days (p = 0.015). Hospital mortality was not significantly different (25/31; 81% versus 29/31; 93%; p = 0.26) after matching. The median time from mechanical ventilation withdrawal until death was 2 days [0 - 5], and 10/31 (32%) patients died within 24 hours after mechanical ventilation withdrawal.

conclusionIn this Brazilian report, mechanical ventilation withdrawal represented 11% of all patients with treatment limitations and was not associated with increased hospital mortality after propensity score matching on relevant covariates.

Indexed as

Intensive Care UnitsRespiration, ArtificialHospital MortalityHumansLength of StayRetrospective Studies

Identifiers

PMID33470354
PMCPMC7853674

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.