ArticleArquivos brasileiros de cardiologia2020
Relationship between Pulse Wave Velocity and Cardiovascular Biomarkers in Patients with Risk Factors.
Article in Arquivos brasileiros de cardiologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Early Carotid Structural and Functional Changes Associated With Elevated Blood Pressure in Children: A Multimodal Ultrasound Study.Journal of clinical hypertension (Greenwich, Conn.) · 2026Observational
- Abnormal vascular thickness and stiffness in young adults with type 1 diabetes: new insights from cutting-edge ultrasound modalities.Cardiovascular diabetology · 2024Observational
- The usefulness of SAGE score in predicting high pulse wave velocity in hypertensive patients: a retrospective cohort study.Frontiers in cardiovascular medicine · 2024Article
- Pulse Wave Velocity of 8.2 m/s as a Threshold Associated with Cardiovascular Target Organ Damage Presence.Arquivos brasileiros de cardiologia · 2023Article
- Association of Carotid-Femoral Pulse Wave Velocity and Ejection Duration with Target Organ Damage.Reviews in cardiovascular medicine · 2023Article
- Pharmacological treatment of hypertension guided by peripheral or central blood pressure: a comparison between the two strategies.Frontiers in cardiovascular medicine · 2023Article
- A SAGE score cutoff that predicts high-pulse wave velocity as measured by oscillometric devices in Brazilian hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Chronological Age or Biological Age, Mainly a Matter of Lifestyle.Arquivos brasileiros de cardiologia · 2021Article
- Parameters of Central Hemodynamics as New Biomarkers of Cardiovascular Risk.Arquivos brasileiros de cardiologia · 2020Article
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8 authors.
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Abstract
backgroundThe relationship between pulse wave velocity (PWV) and biomarkers of structural changes of the left ventricle and carotid arteries remains poorly understood.
objectiveTo investigate the relationship between PWV and these biomarkers.
methodsThis was an analytical, retrospective, cross-sectional study. Medical records of patients with diabetes mellitus, dyslipidemia, and pre-hypertension or hypertension, who underwent central blood pressure (CBP) measurement using Mobil-O-Graph®, and carotid doppler or echocardiography three months before and after the CBPM were analyzed. Statistical analysis was performed using Pearson or Spearman correlation, linear bivariate and multiple regression analysis, and the t test (independent) or Mann-Whitney test. A p <0.05 indicated statistical significance.
resultsMedical records of 355 patients were analyzed, mean age 56.1 (±14.8) years, 51% male. PWV was correlated with intima-media thickness (IMT) of carotids (r=0.310) and left ventricular septal thickness (r=0.191), left ventricular posterior wall thickness (r=0.215), and left atrial diameter (r=0.181). IMT was associated with PWV adjusted by age and peripheral systolic pressure (p=0.0004); IMT greater than 1 mm increased the chance of having PWV above 10 m/s by 3.94 times. PWV was significantly higher in individuals with left ventricular hypertrophy (p=0.0001), IMT > 1 mm (p=0.006), carotid plaque (p=0.0001), stenosis ≥ 50% (p=0.003), and target-organ damage (p=0.0001).
conclusionPWV was correlated with IMT and echocardiographic parameters, and independently associated with IMT. This association was stronger in individuals with left ventricular hypertrophy, increased IMT, carotid plaque, stenosis ≥ 50%, and target organ damage. (Arq Bras Cardiol. 2020; 115(6):1125-1132).
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