Evidence map›Paper›PMID 33470174›Full record

ArticleBioengineered2021

Effect of fed-batch and chemostat cultivation processes of

Yufu Zhang, Haibo Xiong, Zhichao Chen, Yunpeng Fu, Qingyang Xu, Ning Chen

Abstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Optimization of levan biosynthesis fromBiotechnology reports (Amsterdam, Netherlands) · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yufu ZhangCollege of Biotechnology, Tianjin University of Science & Technology , Tianjin, P. R. China.
Haibo XiongCollege of Biotechnology, Tianjin University of Science & Technology , Tianjin, P. R. China.
Zhichao ChenCollege of Biotechnology, Tianjin University of Science & Technology , Tianjin, P. R. China.
Yunpeng FuCollege of Biotechnology, Tianjin University of Science & Technology , Tianjin, P. R. China.
Qingyang XuCollege of Biotechnology, Tianjin University of Science & Technology , Tianjin, P. R. China.ORCID 0000-0003-1619-3508
Ning ChenCollege of Biotechnology, Tianjin University of Science & Technology , Tianjin, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most of the current industrial processes for L-leucine production are based on fermentation, usually in fed-batch operation mode. Although the culture technology has advanced in recent decades, the process still has significant drawbacks. To solve these problems, we investigated the effects of chemostat culture conditions on the production of L-leucine by

Indexed as

AlanineBatch Cell Culture TechniquesBioreactorsCorynebacterium glutamicumCulture MediaLeucineMetabolic EngineeringAlanineCulture MediaLeucinechemostatCorynebacterium glutamicumfed-batchL-alanineL-leucine

Identifiers

PMID33470174
PMCPMC8806242

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.