ArticleJournal of the American Geriatrics Society2021
Validation of Perceived Mental Fatigability Using the Pittsburgh Fatigability Scale.
Article in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- The "Reducing Inflammation for Greater Health Trial (RIGHT)" Study-Concept, Rationale, and Design.Journal of the American Geriatrics Society · 2026Trial
- Evaluation of the construct validity of the Michigan Fatigability Index (MIFI) short forms: a cross-sectional survey study.Journal of patient-reported outcomes · 2026Article
- The right tool for the job: a comparative psychometric analysis of commonly used perceived fatigue and fatigability measures in multiple sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Loneliness and sarcopenia in aged care: the mediating role of fatigability.Innovation in aging · 2026Article
- Psychometric properties of the Pittsburgh Fatigability Scale for assessing physical and mental fatigability in Brazilian older adults (PFS-Brasil).Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026Article
- Sleep quality and possible sarcopenia in community-dwelling older adults: physical and mental fatigability as mediators.BMC geriatrics · 2025Article
- The prevalence and associated factors of perceived physical and mental fatigability among older adults in regional China.BMC geriatrics · 2025Article
- The interplay between perceived fatigability, intrinsic capacity, and physical activity: network analysis in a British birth cohort study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- The association of physical activity with perceived fatigability among community-dwelling older adults aged ≥60 years in regional China.Preventive medicine reports · 2025Article
- Using Wearable Devices to Examine the Associations of Sedentary Behavior with Perceived and Performance Fatigability Among Older Adults: The Study of Muscle, Mobility and Aging (SOMMA).Sensors (Basel, Switzerland) · 2025Article
- Sex differences in the association between skeletal muscle energetics and perceived physical fatigability: the Study of Muscle, Mobility and Aging (SOMMA).GeroScience · 2025Article
- Cross-cultural translation, validation, and responsiveness of the Pittsburgh Fatigability Scale - Italian version (PFS-I) in a mixed-sample of older adults.BMC geriatrics · 2024Article
- Role of Walking Energetics and Perceived Fatigability Differs by Gait Speed: The Study of Muscle, Mobility and Aging (SOMMA).The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Associations of depression and perceived physical fatigability with white matter integrity in older adults.Psychiatry research. Neuroimaging · 2024Article
- Usual-paced 400 m long distance corridor walk estimates cardiorespiratory fitness among older adults: The Study of Muscle, Mobility and Aging.Journal of the American Geriatrics Society · 2024Article
- The association between frailty and perceived physical and mental fatigability: The Long Life Family Study.Journal of the American Geriatrics Society · 2024Article
- Validation of the Pittsburgh Performance Fatigability Index in the Study of Muscle, Mobility and Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Muscle mass, strength, power and physical performance and their association with quality of life in older adults, the Study of Muscle, Mobility and Aging (SOMMA).medRxiv : the preprint server for health sciences · 2023Article
- The Study of Muscle, Mobility and Aging (SOMMA): A Unique Cohort Study About the Cellular Biology of Aging and Age-related Loss of Mobility.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
objectivesEstablish reliability, concurrent and convergent validity of the Pittsburgh Fatigability Scale (PFS) Mental subscale.
designCross-sectional.
settingOlder adults from two University of Pittsburgh registries, Baltimore Longitudinal Study of Aging (BLSA), and Long Life Family Study (LLFS).
participantsPFS Mental subscale validation was conducted using three cohorts: (1) Development Sample (N = 664, 59.1% women, age 74.8 ± 6.4 years, PFS Mental scores 10.3 ± 9.1), (2) Validation Sample I-BLSA (N = 430, 51.9% women, age 74.5 ± 8.2 years, PFS Mental scores 9.4 ± 7.9), and (3) Validation Sample II-LLFS (N = 1,917, 54.5% women, age 72.2 ± 9.3 years, PFS Mental scores 7.5 ± 8.2). MEASUREMENTS: Development Sample, Validation Sample I-BLSA, and Validation Sample II-LLFS participants self-administered the 10-item Pittsburgh Fatigability Scale. Validation Sample II-LLFS completed cognition measures (Trail Making Tests A and B), depressive symptomatology (Center for Epidemiologic Studies-Depression Scale, CES-D), and global fatigue from two CES-D items.
resultsIn the Development Sample and Validation Sample I-BLSA, confirmatory factor analysis showed all 10 items loaded on two factors: social and physical activities (fit indices: SRMSR = 0.064, RMSEA = 0.095, CFI = 0.91). PFS Mental scores had strong internal consistency (Cronbach's α = 0.85) and good test-retest reliability (ICC = 0.78). Validation Sample II-LLFS PFS Mental scores demonstrated moderate concurrent and construct validity using Pearson (r) or Spearman (ρ) correlations against measures of cognition (Trail Making Tests A (r = 0.14) and B (r = 0.17) time), depressive symptoms (r = 0.31), and global fatigue (ρ = 0.21). Additionally, the PFS Mental subscale had strong convergent validity, discriminating according to established clinical or cognitive testing cut points, with differences in PFS Mental scores ranging from 3.9 to 7.6 points (all P < .001). All analyses were adjusted for family relatedness, field center, age, sex, and education.
conclusionsThe validated PFS Mental subscale may be used in clinical and research settings as a sensitive, one-page self-administered tool of perceived mental fatigability in older adults.
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