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ArticleMycopathologia2021

Multilocus Sequence Typing of Clinical Isolates of Cryptococcus from India.

Immaculata Xess, Mragnayani Pandey, Yubhisha Dabas, Reshu Agarwal, Shukla Das, Padma M V Srivastava, Rajeev Thakur, Shyama Sharma, Prashant Mani, Ashutosh Biswas and 9 more

Abstract read
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In one paragraph

Article in Mycopathologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Sequence Types ofPathogens (Basel, Switzerland) · 2026
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  4. Article
  5. Article
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  7. Article
  8. Article
  9. Invasive Fungal Infections 2021.Journal of fungi (Basel, Switzerland) · 2022
    Article
  10. Journal of fungi (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Article
  13. Central Nervous System Cryptococcosis due toCurrent tropical medicine reports · 2022
    Review
  14. Article
  15. Cryptococcosis and Cryptococcus.Mycopathologia · 2021
    Article
  16. Associations betweenJournal of fungi (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Immaculata XessDepartment of Microbiology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, 110029, India. immaxess@gmail.com.ORCID http://orcid.org/0000-0002-6218-2175
Mragnayani PandeyDepartment of Microbiology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, 110029, India.
Yubhisha DabasDepartment of Microbiology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, 110029, India.
Reshu AgarwalDepartment of Microbiology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, 110029, India.
Shukla DasDepartment of Microbiology, University College of Medical Sciences (UCMS) & Guru TegBahadur (GTB) Hospital, New Delhi, Delhi, India.
Padma M V SrivastavaDepartment of Neurology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, India.
Rajeev ThakurDepartment of Microbiology, Institute of Human Behavior& Allied Sciences (IHBAS), Delhi, India.
Shyama SharmaDepartment of Microbiology, University College of Medical Sciences (UCMS) & Guru TegBahadur (GTB) Hospital, New Delhi, Delhi, India.
Prashant ManiDepartment of Microbiology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, 110029, India.
Ashutosh BiswasDepartment of Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, India.
Dipankar BhowmikDepartment of Nephrology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, India.
Bimal K DasDepartment of Microbiology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, 110029, India.
Rakesh SinghDepartment of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Preetilata PandaDepartment of Microbiology, Maharaja Krishna Chandra Gajapati (MKCG) Medical College & Hospital, Brahmapur, Odisha, India.
Gagandeep SinghDepartment of Microbiology, All India Institute of Medical Sciences (AIIMS), New Delhi, Delhi, 110029, India.
A C PhukanDepartment of Microbiology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), Shillong, Meghalaya, India.
Margaret YhomeDepartment of Microbiology, Naga Hospital Authority Kohima (NHAK), Kohima, Nagaland, India.
Chithra ValsanDepartment of Microbiology, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India.
Anupma Jyoti KindoDepartment of Microbiology, Sri Ramachandra Medical College and Research Institute (SRMC & RI), Chennai, Tamil Nadu, India.

Funding

Department of Biotechnology, India BT/PR5193/MED/29/463/2012
6 · The paper itself

Abstract

Cryptococcosis is a life-threatening infection caused by Cryptococcus neoformans and C. gattii species complex. In the present study, to understand the molecular epidemiology of 208 clinical isolates of Cryptococcus from different parts of India, multilocus sequence typing (MLST) using ISHAM MLST consensus scheme for C. neoformans/C. gattii species complex was used. MLST analysis yielded a total of 10 Sequence Types (STs)-7 STs for C. neoformans and 3 for C. gattii species complex. The majority of isolates identified as C. neoformans belonged to molecular type VNI with predominant STs 31 and 93. Only 3 isolates of C. gattii species complex were obtained, belonging to ST58 and ST215 of VGI and ST69 of VGIV. Phylogenetic analysis revealed less diversity among the clinical Indian isolates compared to the global MLST database. No association between prevalent STs and HIV status, geographical origin or minimum inhibitory concentration (MIC) could be established.

Indexed as

CryptococcosisCryptococcus gattiiCryptococcus neoformansGenotypeHumansIndiaMultilocus Sequence TypingMycological Typing TechniquesPhylogenyAntifungal susceptibilityCryptococcusIndiaMultilocus sequence typing (MLST)

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.