Evidence map›Paper›PMID 33469817›Full record

ArticleLa Radiologia medica2021

Deep vein thrombosis in COVID-19 patients in general wards: prevalence and association with clinical and laboratory variables.

Anna Maria Ierardi, Nicola Gaibazzi, Domenico Tuttolomondo, Stefano Fusco, Vincenzo La Mura, Flora Peyvandi, Stefano Aliberti, Francesco Blasi, Diletta Cozzi, Gianpaolo Carrafiello and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

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  6. Exploring Radiologists' Burnout in the COVID-19 Era: A Narrative Review.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Anna Maria IerardiRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy. amierardi@yahoo.it.ORCID http://orcid.org/0000-0002-3033-9713
Nicola GaibazziCardiology Department, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Domenico TuttolomondoCardiology Department, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Stefano FuscoSchool of Radiology, University of Milan, Milan, Italy.
Vincenzo La MuraFondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, U.O.C. Medicina Generale Emostasi e Trombosi, University of Milan, Milan, Italy.
Flora PeyvandiFondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, U.O.C. Medicina Generale Emostasi e Trombosi, University of Milan, Milan, Italy.
Stefano AlibertiUOC Pneumologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Francesco BlasiUOC Pneumologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Diletta CozziDepartment of Radiology, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Gianpaolo CarrafielloCardiology Department, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Massimo De FilippoDepartment of Medicine and Surgery (DiMeC), Unit of Radiology, University of Parma, Parma, Italy.
University of Milan · ITOspedale di Parma · ITAzienda Ospedaliero-Universitaria Careggi · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreliminary reports suggest a hypercoagulable state in COVID-19. Deep vein thrombosis (DVT) is perceived as a frequent finding in hospitalized COVID-19 patients, but data describing the prevalence of DVT are lacking.

objectivesWe aimed to report the prevalence of DVT in COVID-19 patients in general wards, blinded to symptoms/signs of disease, using lower extremities duplex ultrasound (LEDUS) in random patients. We tested the association of DVT with clinical, laboratory and inflammatory markers and also reported on the secondary endpoint of in-hospital mortality. PATIENTS/

methodsn  = 263 COVID-19 patients were screened with LEDUS between March 01, 2020 and April 05, 2020 out of the overall n = 1012 admitted with COVID-19.

resultsDVT was detected in n = 67 screened patients (25.5%), n = 41 patients (15.6%) died during the index hospitalization. Multiple logistic regression demonstrated that only C-reactive protein (odds ratio 1.009, 95% CI 1.004-1.013, p < 0.001) was independently associated with the presence of DVT at LEDUS. Both age (odds ratio 1.101, 95% CI 1.054-1.150, p < 0.001) and C-reactive protein (odds ratio 1.012, 95% CI 1.006-1.018, p < 0.001) were instead significantly independently associated with in-hospital mortality.

conclusionsThe main study finding is that DVT prevalence in COVID-19 patients admitted to general wards is 25.5%, suggesting it may be reasonable to screen COVID-19 patients for this potentially severe but treatable complication, and that inflammation, measured with serum C-reactive protein, is the main variable associated with the presence of DVT, where all other clinical or laboratory variables, age or D-dimer included, are instead not independently associated with DVT.

Indexed as

AgedCOVID-19COVID-19 TestingCross-Sectional StudiesFemaleHospitalsHumansLower ExtremityMaleMiddle AgedPrevalenceUltrasonography, Doppler, DuplexVenous ThrombosisCOVID-19C-reactive proteinDeep vein thrombosisDuplex ultrasoundScreening

Identifiers

PMID33469817
PMCPMC7815188
OpenAlexW3124066102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.