Evidence map›Paper›PMID 33469664›Full record

ReviewOperative neurosurgery (Hagerstown, Md.)2021

Bone Flap Resorption in Pediatric Patients Following Autologous Cranioplasty.

David S Hersh, Hanna J Anderson, Graeme F Woodworth, Jonathan E Martin, Yusuf M Khan

Abstract readReview
In one paragraph

Review in Operative neurosurgery (Hagerstown, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Bone flap fixation with a polymeric clamp-like device in pediatric patients: a safe and effective method that allows bone growth and fusion.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David S HershDivision of Neurosurgery, Connecticut Children's, Hartford, Connecticut.
Hanna J AndersonConnecticut Convergence Institute for Translation in Regenerative Engineering, UConn Health, Farmington, Connecticut.
Graeme F WoodworthDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland.
Jonathan E MartinDivision of Neurosurgery, Connecticut Children's, Hartford, Connecticut.
Yusuf M KhanConnecticut Convergence Institute for Translation in Regenerative Engineering, UConn Health, Farmington, Connecticut.

Funding

Transdermal Mechanical Loading for Cell Therapy-Based Bone RepairR01AR073206 · NIAMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI KHAN, YUSUF M · 2018 to 2023
$1.7M
NIAMS NIH HHS R01 AR073206
6 · The paper itself

Abstract

Following a decompressive craniectomy, the autologous bone flap is generally considered the reconstructive material of choice in pediatric patients. Replacement of the original bone flap takes advantage of its natural biocompatibility and the associated low risk of rejection, as well as the potential to reintegrate with the adjacent bone and subsequently grow with the patient. However, despite these advantages and unlike adult patients, the replaced calvarial bone is more likely to undergo delayed bone resorption in pediatric patients, ultimately requiring revision surgery. In this review, we describe the materials that are currently available for pediatric cranioplasty, the advantages and disadvantages of autologous calvarial replacement, the incidence and classification of bone resorption, and the clinical risk factors for bone flap resorption that have been identified to date.

Indexed as

Bone ResorptionDecompressive CraniectomyAdultChildHumansRetrospective StudiesSkullSurgical FlapsAseptic necrosisCraniectomyCranioplastyOsteolysisPediatricResorption

Identifiers

PMID33469664
PMCPMC8046585

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.