Evidence map›Paper›PMID 33469518›Full record

ArticleFrontiers in cellular and infection microbiology2020

Comparison of Blood Bacterial Communities in Periodontal Health and Periodontal Disease.

David C Emery, Tanya L Cerajewska, Joon Seong, Maria Davies, Alex Paterson, Shelley J Allen-Birt, Nicola X West

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. [The Role of Salivary Microbiota in Oral and Systemic Disease Development and Diagnosis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Research advance in correlation between childhood asthma and gut microbiota.Frontiers in cellular and infection microbiology · 2025
    Review
  9. Review
  10. Effects ofFrontiers in physiology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Bacteria in the blood of healthy stray dogs infested by ticks in northern Mexico.Journal of advanced veterinary and animal research · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

David C EmeryBristol Medical School, Translational Health Sciences, Learning & Research, Southmead Hospital, Bristol, United Kingdom.
Tanya L CerajewskaPeriodontology, Bristol Dental School, University of Bristol, Bristol, United Kingdom.
Joon SeongPeriodontology, Bristol Dental School, University of Bristol, Bristol, United Kingdom.
Maria DaviesPeriodontology, Bristol Dental School, University of Bristol, Bristol, United Kingdom.
Alex PatersonUniversity of Bristol Genomics Facility, School of Biological Sciences, Bristol, United Kingdom.
Shelley J Allen-BirtBristol Medical School, Translational Health Sciences, Learning & Research, Southmead Hospital, Bristol, United Kingdom.
Nicola X WestPeriodontology, Bristol Dental School, University of Bristol, Bristol, United Kingdom.
University Of Bristol Dental Hospital · GBSouthmead Hospital · GBGenomics (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of Next Generation Sequencing (NGS) techniques has generated a wide variety of blood microbiome data. Due to the large variation in bacterial DNA profiles between studies and the likely high concentrations of cell-free bacterial DNA in the blood, it is still not clear how such microbiome data relates to viable microbiota. For these reasons much remains to be understood about the true nature of any possible healthy blood microbiota and of bacteraemic events associated with disease. The gut, reproductive tracts, skin, and oral cavity are all likely sources of blood-borne bacteria. Oral bacteria, especially those associated with periodontal diseases, are also commonly associated with cardiovascular diseases such as infective endocarditis, and also have been linked to rheumatoid arthritis and Alzheimer's disease. Periodontal treatment, dental probing, and toothbrushing have been shown to cause transient bacteraemia and oral bacteria from the phyla Firmicutes (e.g.

Indexed as

MicrobiotaPeriodontal DiseasesPeriodontitisBacteriaDNA, BacterialHumansPhylogenyDNA, Bacterialbacteraemiainflammatory diseasesMolYsisoral bacteriaperiodontitis

Identifiers

PMID33469518
PMCPMC7813997
OpenAlexW3109194399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.