ArticleInternational journal of ophthalmology2021
Corneal epithelial thickness analysis of forme fruste keratoconus with optical coherence tomography.
Article in International journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Regional corneal epithelial thickness and asymmetry patterns in early keratoconus versus regular astigmatism using MS-39 anterior segment OCT: a comparative cross-sectional study.BMC ophthalmology · 2026Article
- Effect of Accelerated Epi-Off Crosslinking on Optical Quality, Corneal Aberrations, and Epithelial Wavefront During Adolescence.Turkish journal of ophthalmology · 2026Article
- Assessing progression limits in different grades of keratoconus from a novel perspective: precision of measurements of the corneal epithelium.Eye and vision (London, England) · 2024Article
- Corneal Epithelial Thickness Mapping: A Major Review.Journal of ophthalmology · 2024Review
- Keratoconus: imaging modalities and management.Medical hypothesis, discovery & innovation ophthalmology journal · 2024Review
- Systemic and Ocular Associations of Keratoconus.Expert review of ophthalmology · 2024Article
- Comparison of corneal measurements in normal and keratoconus eyes using Anterior Segment Optical Coherence Tomography (AS-OCT) and Pentacam HR topographer.BMC ophthalmology · 2023Observational
- Biomechanics of keratoconus: Two numerical studies.PloS one · 2023Article
- Understanding Corneal Epithelial Thickness Mapping.Middle East African journal of ophthalmologyReview
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo explore the significance of corneal epithelial thickness analysis in diagnosing early keratoconus.
methodsThere were 26 clinical keratoconus, 21 forme fruste keratoconus, 40 high corneal astigmatism (ΔK) and 40 low ΔK eyes involved in the study. Fourier-domain optical coherence tomography was used to measure the corneal epithelial thickness of four groups. The morphological features of topographic map and the thickness of corneal epithelial thinnest point were analyzed. The distribution curve of corneal epithelial thickness at 45°, 90°, and 135° axial directions that are through the pupil center was also analyzed. One-way ANOVA was performed to compare the data.
resultsThe topographic map of forme fruste keratoconus corneal epithelial thickness was uniformity shape; crater shape existed only in clinical keratoconus group; and central island shape mainly existed in high ΔK group. The thinnest point of corneal epithelial thickness of forme fruste keratoconus group was significantly lower than that of low ΔK group (
conclusionThe analysis of the thinnest point in forme fruste keratoconus corneal epithelium appears earlier than corneal epithelial remodeling. The topographic map of corneal epithelium in high ΔK eyes appears in central island shape, and can be used for the differential diagnosis of early keratoconus.
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