ArticleInternational journal of ophthalmology2021
Leptin's concentration in tears and dry eye: a clinical observational study.
Article in International journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The trial behind it
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Who cites it
5 citing papers in PubMed.
- The Link between Obstructive Sleep Apnea and Dry Eye Disease: Pathophysiology and Current Updates.Ophthalmic research · 2026Review
- Ocular findings of the patients with congenital leptin deficiency under long-term leptin replacement therapy.International journal of ophthalmology · 2025Article
- Preliminary proteomic analysis of human tears in lacrimal adenoid cystic carcinoma and pleomorphic adenoma.International journal of ophthalmology · 2023Article
- Alterations of ocular surface parameters in patients with obstructive sleep apnea syndrome.Frontiers in medicine · 2023Article
- Leptin activates the JAK/STAT pathway to promote angiogenesis in RF/6A cellsInternational journal of ophthalmology · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the concentration of leptin in tears and its correlation with dry eye symptoms and signs.
methodsThe study enrolled individuals (
resultsAge, body mass index (BMI), OSDI scores and cornea fluorescein staining scores showed a negative correlation with leptin concentration in tears (
conclusionThis is the first study measuring leptin concentration in tears. The correlation between leptin concentration and DED symptoms and signs reveal that leptin level correlated with the dry eye, potentially contributing to repair of ocular damage and dry eye improvement.
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Registered trials
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