Evidence map›Paper›PMID 33469427›Full record

ArticleFrontiers in synaptic neuroscience2020

A Picture Worth a Thousand Molecules-Integrative Technologies for Mapping Subcellular Molecular Organization and Plasticity in Developing Circuits.

Jacqueline A Minehart, Colenso M Speer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in synaptic neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jacqueline A MinehartDepartment of Biology, University of Maryland, College Park, MD, United States.
Colenso M SpeerDepartment of Biology, University of Maryland, College Park, MD, United States.
University of Maryland, College Park · US

Funding

Synaptic Transmission in The Rod Pathway of the Mammalian RetinaR01EY017836 · NEI · UNIV OF MARYLAND, COLLEGE PARK · PI Jonathan B Demb, Anastas Popratiloff · 2007 to 2026
$7.2M
Neural Circuits and Synapses for Early Visual ProcessingR01EY014454 · NEI · YALE UNIVERSITY · PI DEMB, JONATHAN B · 2005 to 2022
$6.7M
A molecular connectomics platform for multi-scale analysis of activity-dependent synapse development and plasticityDP2MH125812 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI SPEER, COLENSO MCNAUGHTON · 2020 to 2020
$2.2M
Functional Circuitry of Long-Range Connections in the RetinaR01EY029323 · NEI · YALE UNIVERSITY · PI DEMB, JONATHAN B · 2018 to 2021
$2.0M
NEI NIH HHS R01 EY014454NEI NIH HHS R01 EY017836NEI NIH HHS R01 EY029323NIMH NIH HHS DP2 MH125812
6 · The paper itself

Abstract

A key challenge in developmental neuroscience is identifying the local regulatory mechanisms that control neurite and synaptic refinement over large brain volumes. Innovative molecular techniques and high-resolution imaging tools are beginning to reshape our view of how local protein translation in subcellular compartments drives axonal, dendritic, and synaptic development and plasticity. Here we review recent progress in three areas of neurite and synaptic study

Indexed as

connectomicslocal protein translationneural developmentproteomicssuper-resolution microscopysynaptic plasticitytranscriptomicstranslatomics

Identifiers

PMID33469427
PMCPMC7813761
OpenAlexW3118669967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.