Evidence map›Paper›PMID 33469342›Full record

ReviewPharmacogenomics and personalized medicine2021

Review on Databases and Bioinformatic Approaches on Pharmacogenomics of Adverse Drug Reactions.

Hang Tong, Nga V T Phan, Thanh T Nguyen, Dinh V Nguyen, Nam S Vo, Ly Le

Abstract readReview
In one paragraph

Review in Pharmacogenomics and personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Genetic Determinants inJournal of personalized medicine · 2021
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hang TongSchool of Biotechnology, International University, Ho Chi Minh City, Vietnam.
Nga V T PhanSchool of Biotechnology, International University, Ho Chi Minh City, Vietnam.
Thanh T NguyenDepartment of Translational Biomedical Informatics, Vingroup Big Data Institute, Hanoi, Vietnam.
Dinh V NguyenDepartment of Respiratory, Allergy and Clinical Immunology, Vinmec International Hospital, Hanoi, Vietnam.
Nam S VoDepartment of Translational Biomedical Informatics, Vingroup Big Data Institute, Hanoi, Vietnam.
Ly LeSchool of Biotechnology, International University, Ho Chi Minh City, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmacogenomics has been used effectively in studying adverse drug reactions by determining the person-specific genetic factors associated with individual response to a drug. Current approaches have revealed the significant importance of sequencing technologies and sequence analysis strategies for interpreting the contribution of genetic variation in developing adverse reactions. Advance in next generation sequencing and platform brings new opportunities in validating the genetic candidates in certain reactions, and could be used to develop the preemptive tests to predict the outcome of the variation in a personal response to a drug. With the highly accumulated available data recently, the in silico approach with data analysis and modeling plays as other important alternatives which significantly support the final decisions in the transformation from research to clinical applications such as diagnosis and treatments for various types of adverse responses.

Indexed as

adverse drug reactionscandidate gene approachgenome-wide association studynext generation sequencingpharmacogenomics

Identifiers

PMID33469342
PMCPMC7812041

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.