ReviewClinical, cosmetic and investigational dermatology2021
The Science of Absorbable Poly(L-Lactide-Co-ε-Caprolactone) Threads for Soft Tissue Repositioning of the Face: An Evidence-Based Evaluation of Their Physical Properties and Clinical Application.
Review in Clinical, cosmetic and investigational dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- The Combined Benefits of Definisse™ Revitalise Threads and Definisse [KP1]Life (Basel, Switzerland) · 2026Article
- Evaluation of Parameters Determining the Pull-Out Strength of Poly(L-Lactide-Co-ε-Caprolactone) Barbed Suspension Threads: A Comparative ex vivo Study.Clinical, cosmetic and investigational dermatology · 2026Article
- VectorLift: Anatomically Guided Thread-Lifting Technique With Reduced Pain and Downtime - Results from a Real-World Non-Randomized Comparative Study.Clinical, cosmetic and investigational dermatology · 2026Article
- Variation of the Thread Thickness After Thread Lifting: An Ultrasonographic Evaluation.Journal of cosmetic dermatology · 2025Article
- Material and biological characterization of 3D knitted bioresorbable poly (D,L-lactide) (PLA) and polycaprolactone (PCL) scaffolds for soft tissue regeneration: from fabrication to in vivo performance.Journal of biological engineering · 2025Article
- A Retrospective Observational Study of Combination Treatment of Thread Lift and High-intensity Focused Ultrasound for Facial Aging.Plastic and reconstructive surgery. Global open · 2025Article
- The Rise and Refinement of Breast Thread Lifting: A Contemporary Review.Journal of clinical medicine · 2025Review
- Efficacy of Lifting Threads Composed of Poly(L-Lactide-Co-ε-Caprolactone) Copolymers Coated With Hyaluronic Acid: A Long-Term Study on Biorevitalizing Properties in Skin Remodeling.Journal of cosmetic dermatology · 2025Article
- Pre- and Post-Procedural Considerations and Thread Types for Thread Lifting.Life (Basel, Switzerland) · 2025Review
- Facial Thread Lifting Complications.Journal of cosmetic dermatology · 2025Review
- Real-World Study of Definisse Threads for Facial Reshaping in Indian Patients: REDEFINE FACE Study.Cureus · 2024Article
- Basic concepts in facial and neck thread lifting procedures.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Review
- What are filling (volumizing) threads?Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Review
- Engineering 3D-Printed Bioresorbable Scaffold to Improve Non-Vascularized Fat Grafting: A Proof-of-Concept Study.Biomedicines · 2023Article
- Micro-nanofiber composite biomimetic conduits promote long-gap peripheral nerve regeneration in canine models.Bioactive materials · 2023Article
- Article
- Assessing the Rejuvenation Effectiveness of a Hyaluronic Acid and Amino Acid Mixture in the Periorbital Region.Clinical, cosmetic and investigational dermatology · 2023Article
- A New Complex Minimally Invasive Thread Lift Method for One-Time Three-Step Fixation of the Face and Neck Soft Tissues.Archives of plastic surgery · 2022Article
- Malar reshaping technique using bidirectional barb thread suspension procedure for 3-dimensional aging in Asian faces.International journal of women's dermatology · 2021Article
- Development of an Antimicrobial-Coated Absorbable Monofilament Suture from a Medical-Grade Poly(l-lactide-ACS omega · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of bioabsorbable threads has become a common minimally invasive technique for the nonsurgical lifting of sagged facial tissues. It entails the passage of barbed threads that form a support structure under the skin of the face and neck to mechanically reposition sagging tissue. Poly(L-lactide-co-ε-caprolactone) has long been used as absorbable sutures and as such has a well-demonstrated efficacy and safety profile. This biomaterial also has a well-defined biocompatibility and degradation profile. All studies reviewed in this paper show that thread lifting with absorbable barbed threads is an effective and well-tolerated procedure for correction of ptosis in facial and neck soft tissue and is associated with minor and reversible adverse effects. Most patients and surgeons consider the procedure satisfactory, with good to excellent results. This publication reviews the literature and clinical data supporting the degradation, absorbability, biocompatibility, safety, and effectiveness of these threads when used for tissue repositioning and facial rejuvenation procedures.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.