Evidence map›Paper›PMID 33469327›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2021

Association Between Low Serum Testosterone and the Development of Metabolic Syndrome in Elderly Taiwanese Men.

Shang-Rong Zhong, Han-Hsuan Yang, Cheng-Hsi Liao, Deng-Ho Yang, Shih-Kai Tu, Chia-Lien Hung, Chun-Cheng Liao

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  4. The Metabolic Syndrome, a Human Disease.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shang-Rong ZhongDepartment of Family Medicine, Taichung Armed Forces General Hospital, Taichung, Taiwan.
Han-Hsuan YangDepartment of Family Medicine, Taichung Armed Forces General Hospital, Taichung, Taiwan.
Cheng-Hsi LiaoDivision of Urology, Department of Surgery, Taichung Armed Forces General Hospital, Taichung, Taiwan.
Deng-Ho YangSchool of Medicine, National Defense Medical Center, Taipei, Taiwan.
Shih-Kai TuDepartment of Family Medicine, Taichung Armed Forces General Hospital, Taichung, Taiwan.
Chia-Lien HungDepartment of Medical Education and Research, Taichung Armed Forces General Hospital, Taichung, Taiwan.
Chun-Cheng LiaoDepartment of Family Medicine, Taichung Armed Forces General Hospital, Taichung, Taiwan.ORCID 0000-0002-7508-6297
Taichung Armed Forces General Hospital · TWChina Medical University · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the association between serum testosterone (T) and metabolic syndrome (MS) in different age groups in Taiwanese men. MATERIALS AND

methodsMale participants, regardless of age or any underlying disease, were identified from MJ Health Screening Center in Taiwan from 2007 to 2016 for this cross-sectional study. They were divided into three groups according to age, and further classified according to MS diagnosis. Basic patient characteristics with relevant parameters were obtained. One-way ANOVA of mean T values between different numbers of measures that exceeds the cut-off values of MS components was performed to assess the relationship of T and MS. Logistic regression analysis was also used to estimate the risk for MS with each increment in T, age, and BMI.

resultsA total of 4,931 men were included. The MS group had significantly lower serum T levels compared to the non-MS group in each age group. The one-way ANOVA found the mean value of T was significantly higher in patients without MS component (6.19±2.12 ng/mL) than those with 1-5 MS components (with one MS component: 5.48±2.13 ng/mL, two MS components: 4.93±2.03 ng/mL, three MS components: 4.37±1.60 ng/mL, four MS components: 4.13±2.89 ng/mL, five MS components: 3.74±1.27 ng/mL, and

conclusionLower serum T was strongly associated with MS, with the predictive value increasing with age in Taiwanese men.

Indexed as

hypogonadisminsulin resistancemetabolic syndrometestosterone

Identifiers

PMID33469327
PMCPMC7810670
OpenAlexW3120070769

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.