Evidence map›Paper›PMID 33469281›Full record

ArticleInternational journal of nanomedicine2021

Magnetic Particle Imaging: In vitro Signal Analysis and Lumen Quantification of 21 Endovascular Stents.

Franz Wegner, Anselm von Gladiss, Julian Haegele, Ulrike Grzyska, Malte Maria Sieren, Erik Stahlberg, Thekla Helene Oechtering, Kerstin Lüdtke-Buzug, Joerg Barkhausen, Thorsten M Buzug and 1 more

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  4. Review
  5. Article
  6. Article
  7. Bare-Metal Stent Tracking with Magnetic Particle Imaging.International journal of nanomedicine · 2024
    Article
  8. Article
  9. Review
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  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Franz Wegner *Department of Radiology and Nuclear Medicine, University of Lübeck, Lübeck, Germany.ORCID 0000-0001-5969-3428
Anselm von Gladiss *Institute of Medical Engineering, University of Lübeck, Lübeck, Germany.ORCID 0000-0003-1340-4576
Julian HaegeleDepartment of Radiology and Nuclear Medicine, University of Lübeck, Lübeck, Germany.
Ulrike GrzyskaDepartment of Radiology and Nuclear Medicine, University of Lübeck, Lübeck, Germany.ORCID 0000-0002-0676-5624
Malte Maria SierenDepartment of Radiology and Nuclear Medicine, University of Lübeck, Lübeck, Germany.ORCID 0000-0002-3669-2892
Erik StahlbergDepartment of Radiology and Nuclear Medicine, University of Lübeck, Lübeck, Germany.ORCID 0000-0003-1574-8479
Thekla Helene OechteringDepartment of Radiology and Nuclear Medicine, University of Lübeck, Lübeck, Germany.ORCID 0000-0002-1931-1912
Kerstin Lüdtke-BuzugInstitute of Medical Engineering, University of Lübeck, Lübeck, Germany.
Joerg BarkhausenDepartment of Radiology and Nuclear Medicine, University of Lübeck, Lübeck, Germany.ORCID 0000-0001-8937-1198
Thorsten M BuzugInstitute of Medical Engineering, University of Lübeck, Lübeck, Germany.ORCID 0000-0002-0399-8043
Thomas FriedrichInstitute of Medical Engineering, University of Lübeck, Lübeck, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEndovascular stents are medical devices, which are implanted in stenosed blood vessels to ensure sufficient blood flow. Due to a high rate of in-stent re-stenoses, there is the need of a noninvasive imaging method for the early detection of stent occlusion. The evaluation of the stent lumen with computed tomography (CT) and magnetic resonance imaging (MRI) is limited by material-induced artifacts. The purpose of this work is to investigate the potential of the tracer-based modality magnetic particle imaging (MPI) for stent lumen visualization and quantification.

methodsIn this in vitro study, 21 endovascular stents were investigated in a preclinical MPI scanner. Therefore, the stents were implanted in vessel phantoms. For the signal analysis, the phantoms were scanned without tracer material, and the signal-to-noise-ratio was analyzed. For the evaluation of potential artifacts and the lumen quantification, the phantoms were filled with diluted tracer agent. To calculate the stent lumen diameter a calibrated threshold value was applied.

resultsWe can show that it is possible to visualize the lumen of a variety of endovascular stents without material induced artifacts, as the stents do not generate sufficient signals in MPI. The stent lumen quantification showed a direct correlation between the calculated and nominal diameter (r = 0.98).

conclusionIn contrast to MRI and CT, MPI is able to visualize and quantify stent lumina very accurately.

Indexed as

Endovascular ProceduresMagnetic PhenomenaSignal Processing, Computer-AssistedStentsArtifactsHumansMagnetic Resonance ImagingPhantoms, ImagingSignal-To-Noise RatioTomography, X-Ray Computedartifactsendovascular stentslumen quantificationmagnetic particle imagingsuperparamagnetic iron oxide nanoparticles

Identifiers

PMID33469281
PMCPMC7810673

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.