Evidence map›Paper›PMID 33469188›Full record

ArticlePediatric research2021

Transcutaneous carbon dioxide pattern and trend over time in preterm infants.

Katherine P Sullivan, Heather O White, Lindsay E Grover, Jordi J Negron, Austin F Lee, Lawrence M Rhein

Open access · bronzeAbstract read
In one paragraph

Article in Pediatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. A Wearable Prototype Measuring PtcCOIEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference · 2024
    Article
  2. Transcutaneous COJournal of clinical medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Katherine P SullivanDepartment of Neonatology, University of Massachusetts Medical School, Worcester, MA, USA. Katherine.sullivan@umassmemorial.org.
Heather O WhiteDepartment of Neonatology, University of Massachusetts Medical School, Worcester, MA, USA.
Lindsay E GroverDepartment of Neonatology, University of Massachusetts Medical School, Worcester, MA, USA.
Jordi J NegronDepartment of Neonatology, University of Massachusetts Medical School, Worcester, MA, USA.
Austin F LeeDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Lawrence M RheinDepartment of Neonatology, University of Massachusetts Medical School, Worcester, MA, USA.
University of Massachusetts Chan Medical School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic lung disease remains a burden for extremely preterm infants. The changes in ventilation over time and optimal ventilatory management remains unknown. Newer, non-invasive technologies provide insight into these patterns.

methodsThis single-center prospective cohort study enrolled infants ≤32 0/7 weeks. We obtained epochs of transcutaneous carbon dioxide (TcCO

resultsPatterns of hypercarbia varied based on birth gestational age and post-menstrual age (PMA) (p = 0.03), regardless of respiratory support. Infants receiving the most respiratory support had values 16-21 mmHg higher than those on room air (p < 0.001). Infants born at the youngest gestational ages had the greatest total change but the rate of change was slower (p = 0.049) compared to infants born at later gestational ages. All infants had TcCO

conclusionsHypercarbia improves as infants approached 31-33 weeks PMA. Hypercarbia was the highest in the most immature infants and improved with age and growth despite weaning respiratory support. IMPACT: This study describes the evolution of hypercarbia as very preterm infants grow and develop. The pattern of ventilation is significantly different depending on the gestational age at birth and post-menstrual age. Average transcutaneous carbon dioxide (TCO

Indexed as

Infant, PrematureBlood Gas Monitoring, TranscutaneousCarbon DioxideFemaleHumansInfant, NewbornMaleProspective StudiesCarbon Dioxide

Identifiers

PMID33469188
PMCPMC7814526
OpenAlexW3122334817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.