ArticleCommunications biology2021
Horseshoe crab genomes reveal the evolution of genes and microRNAs after three rounds of whole genome duplication.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Characterization of the Complete Mitochondrial Genome ofAnimals : an open access journal from MDPI · 2026Article
- Pax6 homologs are required for patterning both visual systems of the daddy-longlegs Phalangium opilio.Molecular biology and evolution · 2026Article
- Evolutionary dynamics of the arthropod molting machinery.Molecular biology and evolution · 2026Review
- ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2026Article
- Article
- Anterior-posterior patterning in the chaetognath Spadella cephaloptera informs bilaterian nervous system and tail evolution.Communications biology · 2025Article
- Assessing the Impact of Whole Genome Duplication on Gene Expression and Regulation During Arachnid Development.Genome biology and evolution · 2025Article
- Gene and Genome Duplication in Spiders.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2025Review
- Diversity and evolutionary history of RNA viruses among different horseshoe crab species.Journal of virology · 2025Article
- Article
- The genome of a sea spider corroborates a shared Hox cluster motif in arthropods with a reduced posterior tagma.BMC biology · 2025Article
- Decoding microRNA arm switching: a key to evolutionary innovation and gene regulation.Cellular and molecular life sciences : CMLS · 2025Review
- Whole Genome Duplication in the Genomics Era: The Hidden Gems in Invertebrates?Genome biology and evolution · 2025Review
- Genome Assembly of a Living Fossil, the Atlantic Horseshoe Crab Limulus polyphemus, Reveals Lineage-Specific Whole-Genome Duplications, Transposable Element-Based Centromeres, and a ZW Sex Chromosome System.Molecular biology and evolution · 2025Article
- Modeling habitat distribution and niche overlap of Asian horseshoe crabs: Implications for conservation.PloS one · 2025Article
- A Novel Expression Domain of extradenticle Underlies the Evolutionary Developmental Origin of the Chelicerate Patella.Molecular biology and evolution · 2024Article
- First whole-genome sequence and assembly of the Ecuadorian brown-headed spider monkey (Ateles fusciceps fusciceps), a critically endangered species, using Oxford Nanopore Technologies.G3 (Bethesda, Md.) · 2024Article
- Common misconceptions of speciation.Evolutionary journal of the Linnean Society · 2024Review
- Evolution of the Spider Homeobox Gene Repertoire by Tandem and Whole Genome Duplication.Molecular biology and evolution · 2023Article
- Assessing species coverage and assembly quality of rapidly accumulating sequenced genomes.GigaScience · 2022Article
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26 authors.
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Abstract
Whole genome duplication (WGD) has occurred in relatively few sexually reproducing invertebrates. Consequently, the WGD that occurred in the common ancestor of horseshoe crabs ~135 million years ago provides a rare opportunity to decipher the evolutionary consequences of a duplicated invertebrate genome. Here, we present a high-quality genome assembly for the mangrove horseshoe crab Carcinoscorpius rotundicauda (1.7 Gb, N50 = 90.2 Mb, with 89.8% sequences anchored to 16 pseudomolecules, 2n = 32), and a resequenced genome of the tri-spine horseshoe crab Tachypleus tridentatus (1.7 Gb, N50 = 109.7 Mb). Analyses of gene families, microRNAs, and synteny show that horseshoe crabs have undergone three rounds (3R) of WGD. Comparison of C. rotundicauda and T. tridentatus genomes from populations from several geographic locations further elucidates the diverse fates of both coding and noncoding genes. Together, the present study represents a cornerstone for improving our understanding of invertebrate WGD events on the evolutionary fates of genes and microRNAs, at both the individual and population level. We also provide improved genomic resources for horseshoe crabs, of applied value for breeding programs and conservation of this fascinating and unusual invertebrate lineage.
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