ArticleScientific reports2021
Enlarged adipocytes from subcutaneous vs. visceral adipose tissue differentially contribute to metabolic dysfunction and atherogenic risk of patients with obesity.
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Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
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36 citing papers in PubMed, 49 citations in OpenAlex.
- The Effect of Magnesium Supplementation on Endothelial Function: A Randomised Cross-Over Pilot Study.International journal of environmental research and public health · 2021Trial
- Lactoferrin Deficiency During Lactation Causes Adult Obesity-Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A Novel mechanism for depot-specific leptin gene expression regulation and its persistence after weight loss.iScience · 2026Article
- Evaluation of the relationship between subcutaneous adipose tissue thickness and cardiovascular diseases.Forensic science, medicine, and pathology · 2026Article
- CD36 and Its Role in Obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Role of ChREBP-PPARα-FGF21 Axis in Metabolic Dysfunction of MASLD.International journal of molecular sciences · 2025Article
- Is Adipose Tissue Inflammation the Culprit of Obesity-Associated Comorbidities?Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Review
- Obesity as a Catalyst for Endometrial Hyperplasia and Cancer Progression: A Narrative Review of Epidemiology, Molecular Pathways, and Prevention.Biomedicines · 2025Review
- Molecular Mechanisms Against Successful Weight Loss and Promising Treatment Options in Obesity.Biomedicines · 2025Review
- Unraveling the complexities of diet induced obesity and glucolipid dysfunction in metabolic syndrome.Diabetology & metabolic syndrome · 2025Review
- Density of ectopic fat depots predict distinct biomarkers of glycemic and insulinemic status in persons with HIV.Nutrition & diabetes · 2025Article
- Cinnamon powder intake enhances the effect of caloric restriction on white adipose tissue in male rats.Journal of molecular histology · 2024Article
- Exposure to gestational diabetes mellitus increases subclinical inflammation mediated in part by obesity.Clinical and experimental immunology · 2024Article
- Defective Visceral Adipose Tissue Adaptation in Gestational Diabetes Mellitus.The Journal of clinical endocrinology and metabolism · 2024Article
- The Role of Cdc42 in the Insulin and Leptin Pathways Contributing to the Development of Age-Related Obesity.Nutrients · 2023Review
- Gene coexpression network analysis reveals perirenal adipose tissue as an important target of prenatal malnutrition in sheep.Physiological genomics · 2023Article
- Lupenone-Rich Fraction Derived fromLife (Basel, Switzerland) · 2023Article
- Obesity and the risk of cardiometabolic diseases.Nature reviews. Cardiology · 2023Review
- Pathophysiology of obesity and its associated diseases.Acta pharmaceutica Sinica. B · 2023Review
- Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots.Nature metabolism · 2023Article
Corrections and comments
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Authors and funding
28 authors at 1 institution in 1 country.
Juan Antonio Suárez-CuencaLaboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico. suarej05@gmail.com.
Gustavo De La Peña-Sosa *Laboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Karen De La Vega-Moreno *Laboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Diana Zaineff Banderas-Lares *Laboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Moisés Salamanca-García *Pathology Department, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03104, Mexico City, Mexico.
José Enrique Martínez-Hernández *Laboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Eduardo Vera-Gómez *Laboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Alejandro Hernández-Patricio *Laboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Carlos Ramiro Zamora-Alemán *Laboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Gabriela Alexandra Domínguez-Pérez *Laboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Atzín Suá Ruíz-Hernández *Laboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Juan Ariel Gutiérrez-BuendíaLaboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Alberto Melchor-LópezInternal Medicine Department, H.G.Z. No. 8 "Gilberto Flores Izquierdo", IMSS and Hospital General "Xoco" SS CDMX, 03340, Mexico City, Mexico.
Moisés Ortíz-Fernández *Bariatric Surgery Department, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Jesús Montoya-Ramírez *Bariatric Surgery Department, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Omar Felipe Gaytán-Fuentes *Bariatric Surgery Department, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Angélica Toríz-Ortíz *Diagnostic Imaging Department, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Mario Osorio-Valero *Diagnostic Imaging Department, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Julita Orozco-VázquezDiagnostic Imaging Department, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Sofía Lizeth Alcaráz-EstradaLaboratorio de Medicina Genómica, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Martha Eunice Rodríguez-ArellanoLaboratorio de Medicina Genómica, Hospital Regional "Lic, Adolfo López Mateos", ISSSTE, Mexico City, Mexico.
Brenda Maldonado-ArriagaLaboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Rebeca Pérez-Cabeza de VacaCoordination of Research and Tissue Engineering & Regenerative Medicine Research Group, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Mónica Escamilla-TilchCoordination of Research and Tissue Engineering & Regenerative Medicine Research Group, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Juan Antonio Pineda-JuárezCoordination of Research and Tissue Engineering & Regenerative Medicine Research Group, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Mario Antonio Téllez-GonzálezCoordination of Research and Tissue Engineering & Regenerative Medicine Research Group, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Silvia GarcíaLaboratory of Experimental Metabolism and Clinical Research, Division of Research, Department of Clinical Research, Centro Médico Nacional "20 de Noviembre", ISSSTE, 502, San Lorenzo, Colonia Del Valle, Delegación Benito Juárez, 03100, Mexico City, Mexico.
Paul Mondragón-TeránCoordination of Research and Tissue Engineering & Regenerative Medicine Research Group, Centro Médico Nacional "20 de Noviembre", ISSSTE, 03100, Mexico City, Mexico.
Institute for Social Security and Services for State Workers · MX
Funding
No grant is acknowledged in the PubMed record.
Abstract
Morphological characteristics and source of adipose tissue as well as adipokines may increase cardiometabolic risk. This study aimed to explore whether adipose tissue characteristics may impact metabolic and atherogenic risks. Subcutaneous Adipose Tissue (SAT), Visceral Adipose Tissue (VAT) and peripheral blood were obtained from obese patients submitted to bariatric surgery. Adipose tissue (morphometry), plasma adiponectin, TNF-α, resistin (multiplexing) and biochemical chemistry were analyzed; as well as endothelial dysfunction (Flow Mediated Dilation, FMD) and atherogenesis (Carotid Intima Media Thickness, CIMT). Subgroups divided by adipocyte size and source were compared; as well as correlation and multivariate analysis. Sixty patients 36.6% males, aged 44 years-old, BMI 46.7 kg/m
Indexed as
AdipocytesAdultAtherosclerosisFemaleHumansIntra-Abdominal FatMaleMiddle AgedObesityRisk FactorsSubcutaneous Fat
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